Genome Property Definition Page

AccessionGenProp0039
Namephenylalanine biosynthesis from chorismate
TypePATHWAY
DescriptionThe aromatic amino acid phenylalanine is synthesized via a three step pathway from chorismate. The first two steps, isomerization of chorismate to prephenate and dehydration of prephenate to phenylpyruvate are modelled by specific HMMs. The third step, transamination of phenylpyruvate to form phenylalanine has not been ascribed to a specific transaminase in non-mammals. The YES state for this pathway is therefore indicative of the presence of the two characterized steps.
JCVI RoleAromatic amino acid family
Parent PropertyGenProp0126: amino acid biosynthesis
GenProp0126: amino acid biosynthesis
GenProp0126: amino acid biosynthesis
Web ReferencesKEGG: Phenylalanine Metabolism
IUBMB: Phenylalanine and Tyrosine Biosynthesis
KEGG: Phenylalanine Metabolism
IUBMB: Phenylalanine and Tyrosine Biosynthesis
KEGG: Phenylalanine Metabolism
IUBMB: Phenylalanine and Tyrosine Biosynthesis
Gene Ontology TermGO:0009094: L-phenylalanine biosynthetic process (biological_process)
GO:0009094: L-phenylalanine biosynthetic process (biological_process)
GO:0009094: L-phenylalanine biosynthetic process (biological_process)
GO:0009094: L-phenylalanine biosynthetic process (biological_process)
GO:0009094: L-phenylalanine biosynthetic process (biological_process)
GO:0009094: L-phenylalanine biosynthetic process (biological_process)
GO:0009094: L-phenylalanine biosynthetic process (biological_process)
GO:0009094: L-phenylalanine biosynthetic process (biological_process)
GO:0009094: L-phenylalanine biosynthetic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
chorismate mutase1YESTIGR01791 (HMM): chorismate mutase
TIGR01795 (HMM): chorismate mutase
TIGR01796 (HMM): chorismate mutase
TIGR01797 (HMM): chorismate mutase
TIGR01799 (HMM): chorismate mutase
TIGR01801 (HMM): chorismate mutase
TIGR01802 (HMM): chorismate mutase
TIGR01805 (HMM): chorismate mutase
TIGR01806 (HMM): putative chorismate mutase
TIGR01807 (HMM): chorismate mutase
TIGR01808 (HMM): chorismate mutase
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
chorismate mutase1YESTIGR01791 (HMM): chorismate mutase
TIGR01795 (HMM): chorismate mutase
TIGR01796 (HMM): chorismate mutase
TIGR01797 (HMM): chorismate mutase
TIGR01799 (HMM): chorismate mutase
TIGR01801 (HMM): chorismate mutase
TIGR01802 (HMM): chorismate mutase
TIGR01805 (HMM): chorismate mutase
TIGR01806 (HMM): putative chorismate mutase
TIGR01807 (HMM): chorismate mutase
TIGR01808 (HMM): chorismate mutase
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
chorismate mutase1YESTIGR01791 (HMM): chorismate mutase
TIGR01795 (HMM): chorismate mutase
TIGR01796 (HMM): chorismate mutase
TIGR01797 (HMM): chorismate mutase
TIGR01799 (HMM): chorismate mutase
TIGR01801 (HMM): chorismate mutase
TIGR01802 (HMM): chorismate mutase
TIGR01805 (HMM): chorismate mutase
TIGR01806 (HMM): putative chorismate mutase
TIGR01807 (HMM): chorismate mutase
TIGR01808 (HMM): chorismate mutase
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
GO:0009094: L-phenylalanine biosynthetic process
prephenate dehydratase2YESPF00800 (HMM): prephenate dehydrataseGO:0009094: L-phenylalanine biosynthetic process
prephenate dehydratase2YESPF00800 (HMM): prephenate dehydrataseGO:0009094: L-phenylalanine biosynthetic process
prephenate dehydratase2YESPF00800 (HMM): prephenate dehydrataseGO:0009094: L-phenylalanine biosynthetic process
a transaminase3NOPF00155 (HMM-CLUST): aminotransferase, class I/IIGO:0009094: L-phenylalanine biosynthetic process
a transaminase3NOPF00155 (HMM-CLUST): aminotransferase, class I/IIGO:0009094: L-phenylalanine biosynthetic process
a transaminase3NOPF00155 (HMM-CLUST): aminotransferase, class I/IIGO:0009094: L-phenylalanine biosynthetic process

Parent Properties
AccessionName
GenProp0126amino acid biosynthesis
GenProp0126amino acid biosynthesis
GenProp0126amino acid biosynthesis


Sibling Properties
AccessionName
GenProp0001chorismate biosynthesis via shikimate
GenProp0016selenocysteine system
GenProp0037tryptophan biosynthesis from ribose-5-phosphate
GenProp0045tyrosine biosynthesis from chorismate
GenProp0087arginine biosynthesis from glutatmate via N-acetylglutamate
GenProp0109histidine biosynthesis from ribose-5-phosphate
GenProp0111proline biosynthesis from glutamate
GenProp0117arginine biosynthesis from ornithine, carbamoyl-p and aspartate
GenProp0118ornithine biosynthesis from glutamate, acetylated branch
GenProp0159threonine biosynthesis from aspartate semialdehyde
GenProp0160aspartate semialdehyde biosynthesis from aspartate
GenProp0161methionine biosynthesis from homoserine
GenProp0162isoleucine biosynthesis from threonine and pyruvate
GenProp0163valine biosynthesis from pyruvate
GenProp0164leucine biosynthesis from pyruvate and acetyl-CoA
GenProp0178glycine cleavage system
GenProp0199lysine biosynthesis
GenProp0304cysteine biosynthesis, tRNA-dependent
GenProp0305cysteine biosynthesis
GenProp0729methionine salvage from methylthioadenosine
GenProp0797selenocysteinyl-tRNA, PSTK/SepSecS pathway