Genome Property Definition Page
| Accession | GenProp0143 |
| Name | Leloir pathway (galactose/glucose interconversion) |
| Type | PATHWAY |
| Description | The Leloir pathway can interconvert galactose and glucose, often for galactose degradation. It tends to be found in the Firmicutes. It includes galactokinase, galactose-1-P uridylyltransferase, and UDP-galactose 4-epimerase. |
| JCVI Role | Sugars |
| Parent Property | GenProp0072: central intermediary metabolism |
| Web References | KEGG: Galactose metabolism |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| UDP-glucose 4-epimerase | GalE | YES | TIGR01179 (HMM): UDP-glucose 4-epimerase GalE | |
| galactose-1-phosphate uridylyltransferase | g1P_uri | YES | TIGR00209 (HMM): galactose-1-phosphate uridylyltransferase TIGR01239 (HMM): galactose-1-phosphate uridylyltransferase | |
| galactokinase | gal_kin | YES | TIGR00131 (HMM): galactokinase | |
| aldose 1-epimerase (mutarotase) | mutarot | YES | TIGR02636 (HMM): galactose mutarotase |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0072 | central intermediary metabolism |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0031 | methane utilization |
| GenProp0035 | Calvin cycle |
| GenProp0118 | ornithine biosynthesis from glutamate, acetylated branch |
| GenProp0120 | pentose phosphate cycle |
| GenProp0196 | sulfur metabolism |
| GenProp0202 | nitrogen metabolism |
| GenProp0242 | phosphorus metabolism |
| GenProp0478 | acetyl-CoA -- acetate interconversion via acetyl phosphate |
| GenProp0479 | acetate -- acetyl-CoA interconversions |
| GenProp0689 | glyoxalate conversion to phosphoglycerate |
| GenProp0865 | carbon fixation |