Genome Property Definition Page

Namedissimilatory sulfate reduction
DescriptionDuring anaerobic respiration, sulfate reducing bacteria catalyze the six electron reduction of sulfate to hydrogen sulfide. These sulfate reducers comprise both gram-positive and gram-negative bacteria, as well as archeae [1]. Sulfur oxidizing bacterium, such as Chromatium vinosum, can reversibly catalyze this pathway freeing electrons and ATP [1].
JCVI RoleSulfur metabolism
Parent PropertyGenProp0196: sulfur metabolism
Literature References
[ 1 ]Hipp WM, Pott AS, Thum-Schmitz N, Faath I, Dahl C, Truper HG.  Towards the phylogeny of APS reductases and sirohaem sulfite reductases in sulfate-reducing and sulfur-oxidizing prokaryotes.  Microbiology. 1997 Sep;143 ( Pt 9):2891-902.  PMID 9308173
Web ReferencesMetaCyc Pathway: dissimilatory sulfate reduction
KEGG: Sulfur metabolism
Gene Ontology TermGO:0019419: sulfate reduction (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
sulfate adenylyltransferase1-satYESTIGR00339 (HMM): sulfate adenylyltransferaseGO:0019419: sulfate reduction
Adenylylsulfate reductase, alpha subunit2-AprAYESTIGR02061 (HMM): adenylylsulfate reductase, alpha subunitGO:0019419: sulfate reduction
Adenylylsulfate reductase, beta subunit2-AprBYESTIGR02060 (HMM): adenylylsulfate reductase, beta subunitGO:0019419: sulfate reduction
Sulfite reductase, dissimilatory-type alpha subunit3-DsrAYESTIGR02064 (HMM): sulfite reductase, dissimilatory-type alpha subunitGO:0019419: sulfate reduction
Sulfite reductase, dissimilatory-type beta subunit3-DsrBYESTIGR02066 (HMM): sulfite reductase, dissimilatory-type beta subunitGO:0019419: sulfate reduction

Parent Properties
GenProp0196sulfur metabolism

Sibling Properties
GenProp0030glutathione biosynthesis
GenProp0036biotin biosynthesis
GenProp0140iron-sulfur cluster assembly systems
GenProp0149sulfate reduction to sulfide, assimilatory
GenProp0161methionine biosynthesis from homoserine
GenProp0182reduction of oxidized methionine
GenProp0191sulfate/thiosulfate ABC transporter
GenProp0624sulfite reductase complex, Salmonella/Clostridium type
GenProp0654intracellular sulfur oxidation
GenProp0729methionine salvage from methylthioadenosine