Genome Property Definition Page
Accession | GenProp0160 | |
Name | aspartate semialdehyde biosynthesis from aspartate | |
Type | PATHWAY | |
Description | The aspartate semialdehyde biosynthesis is a two step pathway. [2] The product of this pathway can be used in the lysine biosynthesis or in the pathway leading to homoserine involved in the threonine, isoleucine and methionine biosynthesis. There are three different isozymes differed in their sensitivity to regulation by Lys, Met and Thr in Escherichia coli. [1] | |
JCVI Role | Aspartate family | |
Parent Property | GenProp0126: amino acid biosynthesis | |
Literature References |
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Web References | KEGG: Glycine, serine and threonine metabolism MetaCyc Pathway: homoserine biosynthesis | |
Gene Ontology Term | GO:0009090: homoserine biosynthetic process (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
aspartate kinase | asp_kin | YES | TIGR00656 (HMM): aspartate kinase, monofunctional class TIGR00657 (HMM): aspartate kinase TIGR02078 (HMM): putative Pyrococcus aspartate kinase subunit | GO:0009090: homoserine biosynthetic process GO:0009090: homoserine biosynthetic process GO:0009090: homoserine biosynthetic process |
aspartate-semialdehyde dehydrogenase | asp_smDH | YES | TIGR00978 (HMM): aspartate-semialdehyde dehydrogenase TIGR01296 (HMM): aspartate-semialdehyde dehydrogenase TIGR01745 (HMM): aspartate-semialdehyde dehydrogenase | GO:0009090: homoserine biosynthetic process GO:0009090: homoserine biosynthetic process GO:0009090: homoserine biosynthetic process |
Parent Properties
Accession | Name |
---|---|
GenProp0126 | amino acid biosynthesis |
Sibling Properties
Accession | Name |
---|---|
GenProp0001 | chorismate biosynthesis via shikimate |
GenProp0016 | selenocysteine system |
GenProp0037 | tryptophan biosynthesis from ribose-5-phosphate |
GenProp0039 | phenylalanine biosynthesis from chorismate |
GenProp0045 | tyrosine biosynthesis from chorismate |
GenProp0087 | arginine biosynthesis from glutatmate via N-acetylglutamate |
GenProp0109 | histidine biosynthesis from ribose-5-phosphate |
GenProp0111 | proline biosynthesis from glutamate |
GenProp0117 | arginine biosynthesis from ornithine, carbamoyl-p and aspartate |
GenProp0118 | ornithine biosynthesis from glutamate, acetylated branch |
GenProp0159 | threonine biosynthesis from aspartate semialdehyde |
GenProp0161 | methionine biosynthesis from homoserine |
GenProp0162 | isoleucine biosynthesis from threonine and pyruvate |
GenProp0163 | valine biosynthesis from pyruvate |
GenProp0164 | leucine biosynthesis from pyruvate and acetyl-CoA |
GenProp0178 | glycine cleavage system |
GenProp0199 | lysine biosynthesis |
GenProp0304 | cysteine biosynthesis, tRNA-dependent |
GenProp0305 | cysteine biosynthesis |
GenProp0729 | methionine salvage from methylthioadenosine |
GenProp0797 | selenocysteinyl-tRNA, PSTK/SepSecS pathway |