Genome Property Definition Page

AccessionGenProp0182
Namereduction of oxidized methionine
TypeGUILD
DescriptionMethionine, free or in proteins, is susceptible to oxidation damage. R- and S-conformation enantiomers of methionine sulfoxide can be repaired by different reductases. MsrB (TIGR00357) was previously designated PilB because of altered cytoadherence in a mutant. MsrA and MsrB are sometimes expressed as a fusion protein.
JCVI RoleProtein modification and repair
Parent PropertyGenProp0196: sulfur metabolism
GenProp0196: sulfur metabolism
GenProp0196: sulfur metabolism
GenProp0302: protein repair
GenProp0302: protein repair
GenProp0302: protein repair
GenProp0733: amino acid salvage
GenProp0733: amino acid salvage
GenProp0733: amino acid salvage

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
methionine-S-sulfoxide reductaseMsrAYESTIGR00401 (HMM): peptide-methionine (S)-S-oxide reductase
methionine-S-sulfoxide reductaseMsrAYESTIGR00401 (HMM): peptide-methionine (S)-S-oxide reductase
methionine-S-sulfoxide reductaseMsrAYESTIGR00401 (HMM): peptide-methionine (S)-S-oxide reductase
methionine-R-sulfoxide reductaseMsrBYESTIGR00357 (HMM): methionine-R-sulfoxide reductase
methionine-R-sulfoxide reductaseMsrBYESTIGR00357 (HMM): methionine-R-sulfoxide reductase
methionine-R-sulfoxide reductaseMsrBYESTIGR00357 (HMM): methionine-R-sulfoxide reductase

Parent Properties
AccessionName
GenProp0196sulfur metabolism
GenProp0196sulfur metabolism
GenProp0196sulfur metabolism
GenProp0302protein repair
GenProp0302protein repair
GenProp0302protein repair
GenProp0733amino acid salvage
GenProp0733amino acid salvage
GenProp0733amino acid salvage


Sibling Properties
AccessionName
GenProp0030glutathione biosynthesis
GenProp0036biotin biosynthesis
GenProp0140iron-sulfur cluster assembly systems
GenProp0149sulfate reduction to sulfide, assimilatory
GenProp0155dissimilatory sulfate reduction
GenProp0161methionine biosynthesis from homoserine
GenProp0191sulfate/thiosulfate ABC transporter
GenProp0624sulfite reductase complex, Salmonella/Clostridium type
GenProp0654intracellular sulfur oxidation
GenProp0729methionine salvage from methylthioadenosine