Genome Property Definition Page

AccessionGenProp0194
Namesiroheme biosynthesis from uroporphrinogen-III
TypePATHWAY
JCVI RoleHeme, porphyrin, and cobalamin
Parent PropertyGenProp0184: cofactor biosynthesis
GenProp0820: iron metabolism

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
C-methyltransferase1YESTIGR01469 (HMM): uroporphyrinogen-III C-methyltransferase
oxidase2YESTIGR01470 (HMM): siroheme synthase, N-terminal domain
ferrochelatase3YESTIGR01470 (HMM): siroheme synthase, N-terminal domain

Parent Properties
AccessionName
GenProp0184cofactor biosynthesis
GenProp0820iron metabolism


Sibling Properties
AccessionName
GenProp0001chorismate biosynthesis via shikimate
GenProp0030glutathione biosynthesis
GenProp0036biotin biosynthesis
GenProp0038tetrahydrofolate biosynthesis from GTP and PABA
GenProp0057NAD(P) biosynthesis from L-aspartate and DHAP
GenProp0112riboflavin, FAD and FMN from GTP and ribulose-5-P
GenProp0124pantothenate biosynthesis from aspartate and 2-oxoisovalerate
GenProp0136ubiquinone biosynthesis from chorismate, aerobic
GenProp0140iron-sulfur cluster assembly systems
GenProp0170coenzyme PQQ biosynthesis
GenProp0171coenzyme A biosynthesis from pantothenate
GenProp0220uroporhyrinogen III biosynthesis from 5-aminolevulinate
GenProp0221protoporphyrin IX biosynthesis from uroporphyrinogen III
GenProp0222protoheme from protoporphyrin IX
GenProp0250thiamine: hydroxyethylthiazole from 1-deoxy-D-xylulose-5-phosphate, cysteine, either Tyr or Gly
GenProp02555-aminolevulinate biosynthesis
GenProp0261thiamin pyrophosphate (TPP) de novo biosynthesis
GenProp0274coenzyme B12 biosynthesis - overview
GenProp0300photosynthetic cofactor biosynthesis
GenProp0466molybdopterin biosynthesis
GenProp0752ergothioneine biosynthesis
GenProp0753mycothiol biosynthesis
GenProp0759para-aminobenzoic acid (PABA) biosynthesis from chorismate
GenProp0791coenzyme F420 biosynthesis
GenProp07927,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) biosynthesis
GenProp0836menaquinone biosynthesis
GenProp0860tryptophan tryptophylquinone modification of methylamine dehydrogenase
GenProp0862pyridoxal phosphate biosynthesis, PdxA/PdxJ pathway
GenProp0863pyridoxal phosphate biosynthesis, Pdx1/Pdx2 pathway
GenProp0891coenzyme M biosynthesis
GenProp0917mycofactocin system
GenProp0927bacillithiol biosynthesis
GenProp1064ovothiol biosynthesis
GenProp0627gene pair involved in iron and oxygen metabolism
GenProp0770siderophore biosynthesis
GenProp0774ferric citrate transport system
GenProp0828heme uptake system, NEAT-domain mediated
GenProp0961heme metabolism pair HutWX