Genome Property Definition Page
Accession | GenProp0201 | |
Name | SMC-ScpA-ScpB complex | |
Type | SYSTEM | |
Description | scpA and scpB (segregation and condensation) are proposed [1,2] to act with SMC (structural maintenance of chromosome). SMC is not universal, but is found in Eukaryotes, Archaea, and Bacteria. It is homodimeric in Archaea and Bacteria. A mutation study [2] has shown a role for scpA in DNA repair in addition to its role in chromosome condensation and segregation. Proteins that act with SMC may be termed kleisins; Different SMC/kleisin complexes are termed cohesins and condensins. ScpA and ScpB are clustered in most bacteria. SMC and scpA tend to be clustered in the archaea. | |
JCVI Role | Cell division | |
Parent Property | GenProp0167: cellular growth, organization and division | |
Literature References |
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Gene Ontology Term | GO:0000910: cytokinesis (biological_process) GO:0007059: chromosome segregation (biological_process) GO:0030261: chromosome condensation (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
smc protein | SMC | YES | TIGR02168 (HMM): chromosome segregation protein SMC TIGR02169 (HMM): chromosome segregation protein SMC | GO:0030261: chromosome condensation GO:0007059: chromosome segregation GO:0000910: cytokinesis GO:0030261: chromosome condensation GO:0007059: chromosome segregation GO:0000910: cytokinesis |
ScpA protein | scpA | YES | PF02616 (HMM): ScpA/B protein | GO:0030261: chromosome condensation GO:0007059: chromosome segregation GO:0000910: cytokinesis |
ScpB protein | scpB | YES | TIGR00281 (HMM): segregation and condensation protein B | GO:0030261: chromosome condensation GO:0007059: chromosome segregation GO:0000910: cytokinesis |
Parent Properties
Accession | Name |
---|---|
GenProp0167 | cellular growth, organization and division |
Sibling Properties
Accession | Name |
---|---|
GenProp0049 | spore formation |
GenProp0165 | minCDE system |
GenProp0166 | mreBCD system |
GenProp0173 | cell shape |
GenProp0206 | bacterial cell division septum system |
GenProp0296 | intracytoplasmic membranes |
GenProp0460 | gas vesicle |
GenProp0678 | c-type cytochrome biogenesis, system I |
GenProp0680 | c-type cytochrome biogenesis, system II |