Genome Property Definition Page

Namesignal recognition system, bacterial
DescriptionThe signal recognition system in bacteria includes the signal recognition particle (SRP) receptor FtsY and the SRP itself, which consists of a polypeptide (Ffh) and a structural RNA. Also included in this property are two peptidases. Signal peptidase I cleaves the standard signal peptide, and differs from the signal peptidase used for lipoproteins. Signal peptide peptidases are enzymes that degrade the signal peptides, oligopeptides that may have signaling roles and also that may interfere with protein secretion, left after removal from a nascent protein by some signal peptidase.
JCVI RoleProtein and peptide secretion and trafficking
Parent PropertyGenProp0179: protein transport

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
SRP receptorFtsYYESTIGR00064 (HMM): signal recognition particle-docking protein FtsY
SRP structural RNARNAYESsrp (RNA)
signal peptidase IcleaveYESTIGR02227 (HMM): signal peptidase I
signal peptide peptidasesdegradeNOTIGR00705 (HMM): signal peptide peptidase SppA, 67K type
TIGR00706 (HMM): signal peptide peptidase SppA, 36K type
SRP proteinffhYESTIGR00959 (HMM): signal recognition particle protein

Parent Properties
GenProp0179protein transport

Sibling Properties
GenProp0052type III secretion
GenProp0053type II secretion
GenProp0054type IV secretion
GenProp0059type I secretion
GenProp0127Tat (Sec-independent) protein export
GenProp0207lipoprotein localization system lolABCDE
GenProp0209Sec system preprotein translocase
GenProp0295prokaryotic N-terminal cleavage/methylation, type IV pilin-like
GenProp0326protein sorting system, PEP-CTERM/exosortase (generic)
GenProp0626protein sorting system, sortase type, LPXTG/SrtA class
GenProp0664protein sorting system, sortase type, SrtB class
GenProp0669protein sorting system, putative, exosortase G class
GenProp0735type VI secretion
GenProp0778protein sorting system, GlyGly-CTERM/rhombosortase
GenProp0844accessory Sec system for serine-rich glycoprotein transport
GenProp0845protein sorting system, KxYKxGKxW class
GenProp0859protein sorting system, proteobacterial dedicated sortase type
GenProp0904type VII secretion, Actinobacteria form
GenProp0905type VII secretion, Firmicutes form
GenProp0928OMP chaperone system: SurA-Skp-DegP
GenProp0957protein sorting system, SipW class
GenProp0978protein sorting system, PGF-CTERM/archaeosortase A
GenProp0979protein sorting system, PEF-CTERM/archaeosortase C
GenProp0980protein sorting system, putative, exosortase F class
GenProp0983protein sorting system, VPXXXP-CTERM/archaeosortase B
GenProp0985protein sorting system, VPDSG-CTERM/exosortase C
GenProp0986protein sorting system, VPLPA-CTERM/exosortase D
GenProp0987protein sorting system, cyano-PEP-CTERM class
GenProp0989protein sorting system, VPEID-CTERM/exosortase E
GenProp0993protein sorting system, PIP-CTERM/archaeosortase D
GenProp0996protein sorting system, IPTLxxWG-CTERM/exosortase H
GenProp0999Por secretion system
GenProp1005protein sorting system, putative, exosortase J class
GenProp1054protein sorting system, MSEP-CTERM/exosortase K
GenProp1055protein sorting system, PEFG-CTERM/thaumarchaeosortase
GenProp1074type V secretion
GenProp1087protein sorting system, vault protein/exosortase N