Genome Property Definition Page

AccessionGenProp0214
Nameacetyl-CoA carboxylase complex
TypeSYSTEM
DescriptionThis property describes the acetyl-CoA carboxylase complex, which catalyzes the first committed step of fatty acid biosynthesis, the carboxylation of acetyl-CoA to malonyl-CoA. The four-subunit version usually found in prokaryotes is described by this property.
JCVI RoleBiosynthesis
Parent PropertyGenProp0299: fatty acid biosynthesis
Literature References
[ 1 ]Cronan JE Jr, Waldrop GL.  Multi-subunit acetyl-CoA carboxylases.  Prog Lipid Res. 2002 Sep;41(5):407-35.  PMID 12121720
Gene Ontology TermGO:0003989: acetyl-CoA carboxylase activity (molecular_function)
GO:0009317: acetyl-CoA carboxylase complex (cellular_component)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
acetyl-CoA carboxylase, carboxyl transferase, alpha subunitaccAYESTIGR00513 (HMM): acetyl-CoA carboxylase, carboxyl transferase, alpha subunitGO:0003989: acetyl-CoA carboxylase activity
GO:0009317: acetyl-CoA carboxylase complex
acetyl-CoA carboxylase, biotin carboxyl carrier proteinaccBYESTIGR00531 (HMM): acetyl-CoA carboxylase, biotin carboxyl carrier proteinGO:0003989: acetyl-CoA carboxylase activity
GO:0009317: acetyl-CoA carboxylase complex
acetyl-CoA carboxylase, biotin carboxylaseaccCYESTIGR00514 (HMM): acetyl-CoA carboxylase, biotin carboxylase subunitGO:0003989: acetyl-CoA carboxylase activity
GO:0009317: acetyl-CoA carboxylase complex
acetyl-CoA carboxylase, carboxyl transferase, beta subunitaccDYESTIGR00515 (HMM): acetyl-CoA carboxylase, carboxyl transferase, beta subunitGO:0003989: acetyl-CoA carboxylase activity
GO:0009317: acetyl-CoA carboxylase complex

Parent Properties
AccessionName
GenProp0299fatty acid biosynthesis


Sibling Properties
AccessionName
GenProp0681fatty acid biosynthesis from acetyl-CoA