Genome Property Definition Page

DescriptionAn integron is a system that enables capture and expression of small mobile elements called cassettes. Examples that include large numbers of cassettes, as in Vibrio cholerae El Tor N16961, have been called super-integron, but it is suggested that this term should be deprecated, and no distinct property will be built. An integron should contain an intI gene, of any of several classes, encoding an integrase. It should have a promoter to drive expression, an attI site, ability to incorporate cassettes, and multiple attC sites (also called 59-base element) flanking the cassettes. The attC sites may exhibit high homology to each other in a long integron, but are best recognized by imperfect dyad symmetry at their outer ends. A single genome may have several integrons, and one integron may contain dozens of cassettes. Note that an integron cassette with a defective integron integrase, carried by a Tn7 transposon, is called a class 2 integron.
JCVI RoleOther
Parent PropertyGenProp0066: selfish genetic elements
Literature References
[ 1 ]Hall RM, Stokes HW  Integrons or super integrons?  Microbiology 2004 Jan;150(Pt 1):3-4.  PMID 14702391
Gene Ontology TermGO:0009294: DNA mediated transformation (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
integron integraseintegroYESTIGR02249 (HMM): integron integraseGO:0009294: DNA mediated transformation

Parent Properties
GenProp0066selfish genetic elements

Sibling Properties
GenProp0009integrative genetic element
GenProp0024group I intron
GenProp0025group II intron
GenProp0050prophage regions
GenProp0208phage: major features
GenProp0321toxin-antitoxin system, type II
GenProp0476protein-coding palindromic elements
GenProp1091toxin-antitoxin system, type I
GenProp1092toxin-antitoxin system, type III