Genome Property Definition Page

AccessionGenProp0232
Namephosphonates C-P lyase system
TypeSYSTEM
DescriptionPhosphonates are compounds similar to phosphates, but in which a direct carbon-phosphorous bond replaces a carbon-oxygen-phosphorous linkage. They chelate metals, adsorb strongly to surfaces, and are produced and used industrially to prevent formation of scale on surfaces. The C-P bond is remarkably stable compared to phosphate bonds, and phosphonate utilization is rather uncommon. While some enzymes with fairly narrow specificity are known that cleave the most common naturally occurring phosphonates, this property describes a multisubunit C-P lyase system with broad specificity. The specificity may differ from one case to another, and two systems with overlapping but non-identical specificities may occur in a single genome.
Parent PropertyGenProp0241: phosphonate catabolism
GenProp0241: phosphonate catabolism
Literature References
[ 1 ]White AK, Metcalf WW  Two C-P lyase operons in Pseudomonas stutzeri and their roles in the oxidation of phosphonates, phosphite, and hypophosphite.  J Bacteriol 2004 Jul;186(14):4730-9.  PMID 15231805
[ 2 ]Kononova SV, Nesmeyanova MA  Phosphonates and their degradation by microorganisms.  Biochemistry (Mosc) 2002 Feb;67(2):184-95.  PMID 11952414
[ 1 ]White AK, Metcalf WW  Two C-P lyase operons in Pseudomonas stutzeri and their roles in the oxidation of phosphonates, phosphite, and hypophosphite.  J Bacteriol 2004 Jul;186(14):4730-9.  PMID 15231805
[ 2 ]Kononova SV, Nesmeyanova MA  Phosphonates and their degradation by microorganisms.  Biochemistry (Mosc) 2002 Feb;67(2):184-95.  PMID 11952414
Gene Ontology TermGO:0019700: organic phosphonate catabolic process (biological_process)
GO:0019700: organic phosphonate catabolic process (biological_process)
GO:0019700: organic phosphonate catabolic process (biological_process)
GO:0019700: organic phosphonate catabolic process (biological_process)
GO:0019700: organic phosphonate catabolic process (biological_process)
GO:0019700: organic phosphonate catabolic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
ABC transporter phosphonates ATP-binding proteinPhnCYESTIGR02315 (HMM-CLUST): phosphonate ABC transporter, ATP-binding proteinGO:0019700: organic phosphonate catabolic process
ABC transporter phosphonates ATP-binding proteinPhnCYESTIGR02315 (HMM-CLUST): phosphonate ABC transporter, ATP-binding proteinGO:0019700: organic phosphonate catabolic process
ABC transporter phosphonates-binding proteinPhnDYESTIGR03431 (HMM): phosphonate ABC transporter, periplasmic phosphonate binding proteinGO:0019700: organic phosphonate catabolic process
ABC transporter phosphonates-binding proteinPhnDYESTIGR03431 (HMM): phosphonate ABC transporter, periplasmic phosphonate binding proteinGO:0019700: organic phosphonate catabolic process
ABC transporter phosphonates permeasePhnEYESTIGR01097 (HMM-CLUST): phosphonate ABC transporter, permease protein PhnEGO:0019700: organic phosphonate catabolic process
ABC transporter phosphonates permeasePhnEYESTIGR01097 (HMM-CLUST): phosphonate ABC transporter, permease protein PhnEGO:0019700: organic phosphonate catabolic process
alkylamine acetyltransferase, PhnOPhnONOPF00583 (HMM-CLUST): acetyltransferase, GNAT familyGO:0019700: organic phosphonate catabolic process
alkylamine acetyltransferase, PhnOPhnONOPF00583 (HMM-CLUST): acetyltransferase, GNAT familyGO:0019700: organic phosphonate catabolic process
phosphonate metabolism protein, uncharacterizedphn01NOTIGR03223 (HMM): putative phosphonate metabolism proteinGO:0019700: organic phosphonate catabolic process
phosphonate metabolism protein, uncharacterizedphn01NOTIGR03223 (HMM): putative phosphonate metabolism proteinGO:0019700: organic phosphonate catabolic process
phosphonate metabolism protein, transferase hexapeptide repeat familyphn02NOTIGR03308 (HMM): phosphonate metabolim protein, transferase hexapeptide repeat familyGO:0019700: organic phosphonate catabolic process
phosphonate metabolism protein, transferase hexapeptide repeat familyphn02NOTIGR03308 (HMM): phosphonate metabolim protein, transferase hexapeptide repeat familyGO:0019700: organic phosphonate catabolic process
PhnF transcriptional regulatorphnFNOTIGR02325 (HMM): phosphonate metabolism transcriptional regulator PhnF
PhnF transcriptional regulatorphnFNOTIGR02325 (HMM): phosphonate metabolism transcriptional regulator PhnF
PhnG unchar. phosphonate metabolism proteinphnGYESPF06754 (HMM): phosphonate metabolism protein PhnG
TIGR03293 (HMM): phosphonate C-P lyase system protein PhnG
GO:0019700: organic phosphonate catabolic process
GO:0019700: organic phosphonate catabolic process
PhnG unchar. phosphonate metabolism proteinphnGYESPF06754 (HMM): phosphonate metabolism protein PhnG
TIGR03293 (HMM): phosphonate C-P lyase system protein PhnG
GO:0019700: organic phosphonate catabolic process
GO:0019700: organic phosphonate catabolic process
PhnH unchar. phosphonate metabolism proteinphnHYESPF05845 (HMM): bacterial phosphonate metabolism protein PhnH
TIGR03292 (HMM): phosphonate C-P lyase system protein PhnH
GO:0019700: organic phosphonate catabolic process
GO:0019700: organic phosphonate catabolic process
PhnH unchar. phosphonate metabolism proteinphnHYESPF05845 (HMM): bacterial phosphonate metabolism protein PhnH
TIGR03292 (HMM): phosphonate C-P lyase system protein PhnH
GO:0019700: organic phosphonate catabolic process
GO:0019700: organic phosphonate catabolic process
PhnI unchar. phosphonate metabolism proteinphnIYESPF05861 (HMM): bacterial phosphonate metabolism protein PhnIGO:0019700: organic phosphonate catabolic process
PhnI unchar. phosphonate metabolism proteinphnIYESPF05861 (HMM): bacterial phosphonate metabolism protein PhnIGO:0019700: organic phosphonate catabolic process
PhnJ unchar. phosphonate metaboism proteinphnJYESPF06007 (HMM): phosphonate metabolism protein PhnJGO:0019700: organic phosphonate catabolic process
PhnJ unchar. phosphonate metaboism proteinphnJYESPF06007 (HMM): phosphonate metabolism protein PhnJGO:0019700: organic phosphonate catabolic process
PhnK (ABC-like) C-P lyase protein, putativephnKYESTIGR02323 (HMM): phosphonate C-P lyase system protein PhnKGO:0019700: organic phosphonate catabolic process
PhnK (ABC-like) C-P lyase protein, putativephnKYESTIGR02323 (HMM): phosphonate C-P lyase system protein PhnKGO:0019700: organic phosphonate catabolic process
phosphonate C-P lyase system PhnL subunitphnLYESTIGR02324 (HMM): phosphonate C-P lyase system protein PhnLGO:0019700: organic phosphonate catabolic process
phosphonate C-P lyase system PhnL subunitphnLYESTIGR02324 (HMM): phosphonate C-P lyase system protein PhnLGO:0019700: organic phosphonate catabolic process
PhnM unchar. phosphonate metabolism proteinphnMYESTIGR02318 (HMM): phosphonate metabolism protein PhnMGO:0019700: organic phosphonate catabolic process
PhnM unchar. phosphonate metabolism proteinphnMYESTIGR02318 (HMM): phosphonate metabolism protein PhnMGO:0019700: organic phosphonate catabolic process
PhnN unchar. phosphonate metabolism proteinphnNNOTIGR02322 (HMM): phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnNGO:0019700: organic phosphonate catabolic process
PhnN unchar. phosphonate metabolism proteinphnNNOTIGR02322 (HMM): phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnNGO:0019700: organic phosphonate catabolic process
PhnP unchar. phosphonate metabolism proteinphnPNOTIGR03307 (HMM): phosphonate metabolism protein PhnPGO:0019700: organic phosphonate catabolic process
PhnP unchar. phosphonate metabolism proteinphnPNOTIGR03307 (HMM): phosphonate metabolism protein PhnPGO:0019700: organic phosphonate catabolic process

Parent Properties
AccessionName
GenProp0241phosphonate catabolism
GenProp0241phosphonate catabolism


Sibling Properties
AccessionName
GenProp0710generic phosphonates utilization
GenProp07122-aminoethylphosphonate (AEP) ABC transporter, type I, PhnSTUV
GenProp07202-aminoethylphosphonate utilization
GenProp0736proposed phosphonate catabolism pathway HpnWXZ