Genome Property Definition Page

AccessionGenProp0266
Nametrehalose biosynthesis, TreYZ pathway
TypePATHWAY
DescriptionTrehalose is an alpha,alpha glucose disaccharide that serves as a highly protective osmoprotectant in many species in all three domains of life. Trehalose may also be a component of more complex molecules such as cell wall glycolipids in Actinomycetes. The TreYZ is one of several pathways for trehalose biosynthesis and is dependent on the presence of glycogen-like glucose polymers. It is alternative to the OtsAB (osmotically regulated trehalose synthesis A and B) system. In some species with both, the TreYZ rather then the OtsAB system is induced by osmotic stress.
JCVI RoleBiosynthesis and degradation of polysaccharides
Parent PropertyGenProp0267: osmolyte biosynthesis
GenProp0267: osmolyte biosynthesis
GenProp0267: osmolyte biosynthesis
Literature References
[ 1 ]De Smet KA, Weston A, Brown IN, Young DB, Robertson BD  Three pathways for trehalose biosynthesis in mycobacteria.  Microbiology 2000 Jan;146 ( Pt 1):199-208.  PMID 10658666
[ 2 ]Elbein AD, Pan YT, Pastuszak I, Carroll D  New insights on trehalose: a multifunctional molecule.  Glycobiology 2003 Apr;13(4):17R-27R. Epub 2003 Jan 22.  PMID 12626396
[ 1 ]De Smet KA, Weston A, Brown IN, Young DB, Robertson BD  Three pathways for trehalose biosynthesis in mycobacteria.  Microbiology 2000 Jan;146 ( Pt 1):199-208.  PMID 10658666
[ 2 ]Elbein AD, Pan YT, Pastuszak I, Carroll D  New insights on trehalose: a multifunctional molecule.  Glycobiology 2003 Apr;13(4):17R-27R. Epub 2003 Jan 22.  PMID 12626396
[ 1 ]De Smet KA, Weston A, Brown IN, Young DB, Robertson BD  Three pathways for trehalose biosynthesis in mycobacteria.  Microbiology 2000 Jan;146 ( Pt 1):199-208.  PMID 10658666
[ 2 ]Elbein AD, Pan YT, Pastuszak I, Carroll D  New insights on trehalose: a multifunctional molecule.  Glycobiology 2003 Apr;13(4):17R-27R. Epub 2003 Jan 22.  PMID 12626396
Gene Ontology TermGO:0006970: response to osmotic stress (biological_process)
GO:0006970: response to osmotic stress (biological_process)
GO:0006970: response to osmotic stress (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0006970: response to osmotic stress (biological_process)
GO:0006970: response to osmotic stress (biological_process)
GO:0006970: response to osmotic stress (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0005992: trehalose biosynthetic process (biological_process)
GO:0006970: response to osmotic stress (biological_process)
GO:0006970: response to osmotic stress (biological_process)
GO:0006970: response to osmotic stress (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
maltooligosyltrehalose synthasetreYYESTIGR02401 (HMM): malto-oligosyltrehalose synthaseGO:0005992: trehalose biosynthetic process
GO:0006970: response to osmotic stress
maltooligosyltrehalose synthasetreYYESTIGR02401 (HMM): malto-oligosyltrehalose synthaseGO:0005992: trehalose biosynthetic process
GO:0006970: response to osmotic stress
maltooligosyltrehalose synthasetreYYESTIGR02401 (HMM): malto-oligosyltrehalose synthaseGO:0005992: trehalose biosynthetic process
GO:0006970: response to osmotic stress
malto-oligosyltrehalose trehalohydrolasetreZYESTIGR02402 (HMM): malto-oligosyltrehalose trehalohydrolaseGO:0005992: trehalose biosynthetic process
GO:0006970: response to osmotic stress
malto-oligosyltrehalose trehalohydrolasetreZYESTIGR02402 (HMM): malto-oligosyltrehalose trehalohydrolaseGO:0005992: trehalose biosynthetic process
GO:0006970: response to osmotic stress
malto-oligosyltrehalose trehalohydrolasetreZYESTIGR02402 (HMM): malto-oligosyltrehalose trehalohydrolaseGO:0005992: trehalose biosynthetic process
GO:0006970: response to osmotic stress

Parent Properties
AccessionName
GenProp0267osmolyte biosynthesis
GenProp0267osmolyte biosynthesis
GenProp0267osmolyte biosynthesis


Sibling Properties
AccessionName
GenProp0147glycine betaine biosynthesis from choline
GenProp0264glucosylglycerol biosynthesis
GenProp0265trehalose biosynthesis, OtsAB pathway
GenProp0268ectoine biosynthesis
GenProp0281mannosylglycerate biosynthesis
GenProp0878N(epsilon)-acetyl-beta-lysine biosynthesis
GenProp1070beta-glutamate biosynthesis