Genome Property Definition Page

AccessionGenProp0268
Nameectoine biosynthesis
TypePATHWAY
DescriptionEctoine is a compatible solute used as an osmoprotectant by a number of bacterial species, including Vibrio cholerae, Halomonas variabilis, Bacillus pasteurii, etc. Key enzymes are diaminobutyric acid acetyltransferase (EctA), diaminobutyric acid aminotransferase (EctB), and ectoine synthase (EctC). Ectoine is 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid.
Parent PropertyGenProp0267: osmolyte biosynthesis
Literature References
[ 1 ]Kuhlmann AU, Bremer E  Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp.  Appl Environ Microbiol 2002 Feb;68(2):772-83.  PMID 11823218
Gene Ontology TermGO:0019491: ectoine biosynthetic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
diaminobutyrate acetyltransferaseectAYESTIGR02406 (HMM): diaminobutyrate acetyltransferaseGO:0019491: ectoine biosynthetic process
diaminobutyrate--2-oxoglutarate transaminaseectBYESTIGR02407 (HMM): diaminobutyrate--2-oxoglutarate aminotransferaseGO:0019491: ectoine biosynthetic process
ectoine synthaseectCYESPF06339 (HMM): ectoine synthaseGO:0019491: ectoine biosynthetic process
ectoine hydroxylasehydroxyNOTIGR02408 (HMM): ectoine hydroxylase

Parent Properties
AccessionName
GenProp0267osmolyte biosynthesis


Sibling Properties
AccessionName
GenProp0147glycine betaine biosynthesis from choline
GenProp0264glucosylglycerol biosynthesis
GenProp0265trehalose biosynthesis, OtsAB pathway
GenProp0266trehalose biosynthesis, TreYZ pathway
GenProp0281mannosylglycerate biosynthesis
GenProp0878N(epsilon)-acetyl-beta-lysine biosynthesis
GenProp1070beta-glutamate biosynthesis