| Accession | GenProp0277 |
| Name | cobalt import system (ABC transporter: 3.A.1.18.1) |
| Type | SYSTEM |
| Description | This ABC transporter is important for the import of cobalt ions essential for the biosynthesis of coenzyme B12. In this complex, the solute-binding (CbiN), permease (CbiQ) and ATP-binding (CbiO) subunits are accompanied by a fourth subunit (CbiM) of unknown function, although it is believed to be a membrane-spanning protein. |
| Parent Property | GenProp0274: coenzyme B12 biosynthesis - overview
GenProp0279: cobalt import systems
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| Literature References | [ 1 ]Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS Comparative genomics of the vitamin B12 metabolism and regulation in prokaryotes. J Biol Chem 2003 Oct 17;278(42):41148-59. Epub 2003 Jul 17. PMID 12869542
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| Gene Ontology Term | GO:0006824: cobalt ion transport (biological_process)
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| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|
| cobalamin biosynthesis protein, CbiM | CbiM | YES | TIGR00123 (HMM): cobalamin biosynthesis protein CbiM | GO:0006824: cobalt ion transport
|
| Cobalt transporter, subunit CbiN | CbiN | YES | TIGR01165 (HMM): cobalt transport protein | GO:0006824: cobalt ion transport
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| Cobalt transporter, ATP-binding subunit CbiO | CbiO | YES | TIGR01166 (HMM): cobalt ABC transporter, ATP-binding protein | GO:0006824: cobalt ion transport
|
| Cobalt transporter, permease subunit (CbiQ) | CbiQ | YES | TIGR02454 (HMM): cobalt ABC transporter, permease protein CbiQ | GO:0006824: cobalt ion transport
|
