Genome Property Definition Page

AccessionGenProp0281
Namemannosylglycerate biosynthesis
TypePATHWAY
DescriptionMannosylglycerate is a compatible solute (cf. trehalose, ectoine, sucrose, glucosylglycerol, etc.) that tends to be found in highly thermophilic prokaryotes of various lineages. The more common biosynthetic pathway is a two-step pathway. Mannosyl-3-phosphoglycerate synthase (EC 2.4.1.217) combines GDP-mannose with 3-phospho-D-glycerate. The resultant mannosyl-3-phosphoglycerate is dephosphorylated by mannosyl-3-phosphoglycerate phosphatase (EC 3.1.3.70). The two enzymes are fused in Dehalococcoides ethenogenes, a rare mesophile to have this pathway.
Parent PropertyGenProp0267: osmolyte biosynthesis
GenProp0267: osmolyte biosynthesis
GenProp0267: osmolyte biosynthesis
Literature References
[ 1 ]Empadinhas N, Albuquerque L, Henne A, Santos H, da Costa MS  The bacterium Thermus thermophilus, like hyperthermophilic archaea, uses a two-step pathway for the synthesis of mannosylglycerate.  Appl Environ Microbiol 2003 Jun;69(6):3272-9.  PMID 12788726
[ 1 ]Empadinhas N, Albuquerque L, Henne A, Santos H, da Costa MS  The bacterium Thermus thermophilus, like hyperthermophilic archaea, uses a two-step pathway for the synthesis of mannosylglycerate.  Appl Environ Microbiol 2003 Jun;69(6):3272-9.  PMID 12788726
[ 1 ]Empadinhas N, Albuquerque L, Henne A, Santos H, da Costa MS  The bacterium Thermus thermophilus, like hyperthermophilic archaea, uses a two-step pathway for the synthesis of mannosylglycerate.  Appl Environ Microbiol 2003 Jun;69(6):3272-9.  PMID 12788726

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
mannosyl-3-phosphoglycerate phosphatasempgPYESTIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
TIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
TIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
mannosyl-3-phosphoglycerate phosphatasempgPYESTIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
TIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
TIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
mannosyl-3-phosphoglycerate phosphatasempgPYESTIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
TIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
TIGR02461 (HMM): mannosyl-3-phosphoglycerate phosphatase
mannosyl-3-phosphoglycerate synthasempgSYESTIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase
TIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase
TIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase
mannosyl-3-phosphoglycerate synthasempgSYESTIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase
TIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase
TIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase
mannosyl-3-phosphoglycerate synthasempgSYESTIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase
TIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase
TIGR02460 (HMM): mannosyl-3-phosphoglycerate synthase

Parent Properties
AccessionName
GenProp0267osmolyte biosynthesis
GenProp0267osmolyte biosynthesis
GenProp0267osmolyte biosynthesis


Sibling Properties
AccessionName
GenProp0147glycine betaine biosynthesis from choline
GenProp0264glucosylglycerol biosynthesis
GenProp0265trehalose biosynthesis, OtsAB pathway
GenProp0266trehalose biosynthesis, TreYZ pathway
GenProp0268ectoine biosynthesis
GenProp0878N(epsilon)-acetyl-beta-lysine biosynthesis
GenProp1070beta-glutamate biosynthesis