Genome Property Definition Page

AccessionGenProp0284
Namecobalamin-utilizing enzymes
TypeCOUNTER
DescriptionThis property contains all of the cobalamin (B12) utilizing enzymes which can be detected in a genome.
Parent PropertyGenProp0075: protein modification, prosthetic groups and cofactors
Literature References
[ 1 ]Banerjee R, Ragsdale SW  The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes.  Annu Rev Biochem 2003;72:209-47.  PMID 14527323

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
contains a B12-binding domainBINNOPF02310 (HMM): B12 binding domain
PF02607 (HMM): B12 binding domain
ethanolamine ammonia lyaseEutBCNOPF06751 (HMM): ethanolamine ammonia-lyase, large subunit
PF05985 (HMM): ethanolamine ammonia-lyase, light subunit
methylmalonyl-CoA mutase (5.4.99.1)MMCMNOTIGR00640 (HMM): methylmalonyl-CoA mutase C-terminal domain
TIGR00641 (HMM): methylmalonyl-CoA mutase N-terminal domain
5-methyltetrahydrofolate--homocysteine methyltransferase, B12-dependentMetHNOTIGR02082 (HMM): methionine synthase
tetrahydromethanopterin S-methyltransferase, subunit AMtrANOTIGR01111 (HMM): tetrahydromethanopterin S-methyltransferase, subunit A
reductive dehalogenases, corrin-containingRDHNOTIGR02486 (HMM): reductive dehalogenase
class II ribonucleotide reductaseclII-RNRNOTIGR02505 (HMM): ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent
TIGR02504 (HMM): ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent

Parent Properties
AccessionName
GenProp0075protein modification, prosthetic groups and cofactors

Child Properties
AccessionName
GenProp0288tetrahydromethanopterin S-methyltransferase complex
GenProp0290class II (B12-dependent) ribonucleotide reductase
GenProp0294ethanolamine degradation proteinaceous organelle

Sibling Properties
AccessionName
GenProp0002coenzyme F420 utilization
GenProp0016selenocysteine system
GenProp0061lipoprotein system lgt/lsp/lnt
GenProp0127Tat (Sec-independent) protein export
GenProp0295prokaryotic N-terminal cleavage/methylation, type IV pilin-like
GenProp0726selenium-dependent molybdenum hydroxylase system
GenProp0745lipoyl-protein attachment
GenProp0860tryptophan tryptophylquinone modification of methylamine dehydrogenase
GenProp0918anaerobic sulfatase/maturase system
GenProp0923mycothiol system
GenProp0933bacillithiol utilization
GenProp0938glycine radical enzyme system, YjjI/YjjW pair
GenProp0943pyruvate formate-lyase system
GenProp1080protein O-heptosyltransferase with autotransporter target