Genome Property Definition Page

AccessionGenProp0468
NameEntner-Doudoroff pathway
TypePATHWAY
DescriptionGlucose (in the first two steps of the pentose phosphate pathway) or gluconate (in one step) can be converted to 6-phospho-D-gluconate. The Entner-Doudoroff pathway is the degradation of 6-phospho-D-gluconate in two steps to pyruvate and D-glyceraldehyde 3-phosphate. The D-glyceraldehyde 3-phosphate can then be converted to pyruvate by enzymes from glycolysis. This bacterial pathway is less widespread than glycolysis and is an alternative to the early steps of glycolysis.
JCVI RoleEntner-Doudoroff
Parent PropertyGenProp0070: energy metabolism

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
2-dehydro-3-deoxyphosphogluconate aldolasealdolasYESTIGR01182 (HMM-CLUST): 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
6-phosphogluconate dehydratasedehytaseYESTIGR01196 (HMM): phosphogluconate dehydratase

Parent Properties
AccessionName
GenProp0070energy metabolism


Sibling Properties
AccessionName
GenProp0011methanogenesis
GenProp0023glyoxylate shunt
GenProp0027photosynthesis
GenProp0033TCA cycle
GenProp0120pentose phosphate cycle
GenProp0131electron transport
GenProp0243ATP synthases
GenProp0298fermentation
GenProp0459D-xylose utilization (conversion to D-xylulose-5-phosphate)
GenProp0473arsenite oxidase
GenProp0611aerobic respiration
GenProp0636respiratory nitrate reductase
GenProp0637anaerobic dimethyl sulfoxide reductase
GenProp0638trimethylamine N-oxide reductase system
GenProp0682formate-dependent nitrite reductase, seven-gene type
GenProp0683cytochrome c nitrite reductase NrfHA
GenProp0691glycolysis
GenProp0695cytochrome b558/566
GenProp0723hydrogenase, nickel and F420-dependent
GenProp0737anaerobic glycerol-3-phosphate dehydrogenase complex
GenProp0755pyruvate conversion to propionate, anaerobic, FAD/NAD-regenerating
GenProp0756fumarate reductase complex
GenProp0764DMSO reductase family type II enzyme
GenProp08412-oxoacid:ferredoxin oxidoreductase
GenProp0856bacterio-opsin system
GenProp0914hydrogenase, [FeFe]-dependent
GenProp0915hydrogenase, mono-iron type
GenProp1089B12-dependent trimeric diol/glycerol dehydratase