Genome Property Definition Page
| Accession | GenProp0468 |
| Name | Entner-Doudoroff pathway |
| Type | PATHWAY |
| Description | Glucose (in the first two steps of the pentose phosphate pathway) or gluconate (in one step) can be converted to 6-phospho-D-gluconate. The Entner-Doudoroff pathway is the degradation of 6-phospho-D-gluconate in two steps to pyruvate and D-glyceraldehyde 3-phosphate. The D-glyceraldehyde 3-phosphate can then be converted to pyruvate by enzymes from glycolysis. This bacterial pathway is less widespread than glycolysis and is an alternative to the early steps of glycolysis. |
| JCVI Role | Entner-Doudoroff |
| Parent Property | GenProp0070: energy metabolism |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| 2-dehydro-3-deoxyphosphogluconate aldolase | aldolas | YES | TIGR01182 (HMM-CLUST): 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase | |
| 6-phosphogluconate dehydratase | dehytase | YES | TIGR01196 (HMM): phosphogluconate dehydratase |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0070 | energy metabolism |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0011 | methanogenesis |
| GenProp0023 | glyoxylate shunt |
| GenProp0027 | photosynthesis |
| GenProp0033 | TCA cycle |
| GenProp0120 | pentose phosphate cycle |
| GenProp0131 | electron transport |
| GenProp0243 | ATP synthases |
| GenProp0298 | fermentation |
| GenProp0459 | D-xylose utilization (conversion to D-xylulose-5-phosphate) |
| GenProp0473 | arsenite oxidase |
| GenProp0611 | aerobic respiration |
| GenProp0636 | respiratory nitrate reductase |
| GenProp0637 | anaerobic dimethyl sulfoxide reductase |
| GenProp0638 | trimethylamine N-oxide reductase system |
| GenProp0682 | formate-dependent nitrite reductase, seven-gene type |
| GenProp0683 | cytochrome c nitrite reductase NrfHA |
| GenProp0691 | glycolysis |
| GenProp0695 | cytochrome b558/566 |
| GenProp0723 | hydrogenase, nickel and F420-dependent |
| GenProp0737 | anaerobic glycerol-3-phosphate dehydrogenase complex |
| GenProp0755 | pyruvate conversion to propionate, anaerobic, FAD/NAD-regenerating |
| GenProp0756 | fumarate reductase complex |
| GenProp0764 | DMSO reductase family type II enzyme |
| GenProp0841 | 2-oxoacid:ferredoxin oxidoreductase |
| GenProp0856 | bacterio-opsin system |
| GenProp0914 | hydrogenase, [FeFe]-dependent |
| GenProp0915 | hydrogenase, mono-iron type |