Genome Property Definition Page

AccessionGenProp0473
Namearsenite oxidase
TypePATHWAY
DescriptionThe enzyme designated 1.20.9.1, arsenate reductase (azurin), acts in the biological process of arsenite oxidation for energy metabolism rather than in the reduction of intracellular arsenate to facilitate transport as is the case for arsenate reductases of arsenical resistance systems. The large subunit contains a molybdopterin cofactor, while the small subunit is a Rieske iron-sulfur protein. Azurin is present in some but not all species with arsenite oxidase; it may be replaced by auracyanin or an unrelated redox partner.
JCVI RoleElectron transport
Parent PropertyGenProp0070: energy metabolism
Literature References
[ 1 ]Lebrun E, Brugna M, Baymann F, Muller D, Lievremont D, Lett MC, Nitschke W  Arsenite oxidase, an ancient bioenergetic enzyme.  Mol Biol Evol 2003 May;20(5):686-93.  PMID 12679550
Gene Ontology TermGO:0015975: energy derivation by oxidation of reduced inorganic compounds (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
arsenite oxidase, small (Rieske) subunitRieskeYESTIGR02694 (HMM): arsenite oxidase, small subunitGO:0015975: energy derivation by oxidation of reduced inorganic compounds
azurinazurinNOTIGR02695 (HMM): azurinGO:0015975: energy derivation by oxidation of reduced inorganic compounds
arsenite oxidase, large subunitmolybdoYESTIGR02693 (HMM): arsenite oxidase, large subunitGO:0015975: energy derivation by oxidation of reduced inorganic compounds

Parent Properties
AccessionName
GenProp0070energy metabolism


Sibling Properties
AccessionName
GenProp0011methanogenesis
GenProp0023glyoxylate shunt
GenProp0027photosynthesis
GenProp0033TCA cycle
GenProp0120pentose phosphate cycle
GenProp0131electron transport
GenProp0243ATP synthases
GenProp0298fermentation
GenProp0459D-xylose utilization (conversion to D-xylulose-5-phosphate)
GenProp0468Entner-Doudoroff pathway
GenProp0611aerobic respiration
GenProp0636respiratory nitrate reductase
GenProp0637anaerobic dimethyl sulfoxide reductase
GenProp0638trimethylamine N-oxide reductase system
GenProp0682formate-dependent nitrite reductase, seven-gene type
GenProp0683cytochrome c nitrite reductase NrfHA
GenProp0691glycolysis
GenProp0695cytochrome b558/566
GenProp0723hydrogenase, nickel and F420-dependent
GenProp0737anaerobic glycerol-3-phosphate dehydrogenase complex
GenProp0755pyruvate conversion to propionate, anaerobic, FAD/NAD-regenerating
GenProp0756fumarate reductase complex
GenProp0764DMSO reductase family type II enzyme
GenProp08412-oxoacid:ferredoxin oxidoreductase
GenProp0856bacterio-opsin system
GenProp0914hydrogenase, [FeFe]-dependent
GenProp0915hydrogenase, mono-iron type
GenProp1089B12-dependent trimeric diol/glycerol dehydratase