Genome Property Definition Page
| Accession | GenProp0477 |
| Name | copper resistance system: CopZA |
| Type | SYSTEM |
| Description | This genome property (under development) includes a P-type ATPase copper transporter, a copper response regulatory protein and a copper chaperone. Copper is a cofactor in some enzymes and is reportedly essential in all living organisms, but too much copper can be toxic. A copper response operon may include two copper transporters to achieve copper homeostatis and include efflux capability. Different copper transport systems rely on transporters of other types. |
| JCVI Role | Cations and iron carrying compounds |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| P-type ATPase copper transporter | P_ATP | YES | TIGR01511 (HMM): copper-translocating P-type ATPase | |
| copper chaperone | chaper | YES | TIGR00003 (HMM-CLUST): copper ion binding protein | |
| copper transport repressor | regul | NO | TIGR02698 (HMM): copper transport repressor, CopY/TcrY family |