Genome Property Definition Page

Accession

GenProp0484

Name

F-type conjugation system (type IV secretion) specific components

Type

SYSTEM

Description

A system for the transfer of plasmid DNA between cells via a pilus. This system is a specialized type-IV secretion system.

JCVI Role

Plasmid functions

Parent Property

GenProp0489: F-type conjugation system

Literature References

[ 1 ]Frost LS, Leplae R, Summers AO, Toussaint A  Mobile genetic elements: the agents of open source evolution.  Nat Rev Microbiol 2005 Sep;3(9):722-32.  PMID 16138100
[ 2 ]Lawley TD, Klimke WA, Gubbins MJ, Frost LS  F factor conjugation is a true type IV secretion system.  FEMS Microbiol Lett. 2003 Jul 15;224(1):1-15.  PMID 12855161
[ 3 ]Harris RL, Silverman PM  Tra proteins characteristic of F-like type IV secretion systems constitute an interaction group by yeast two-hybrid analysis.  J Bacteriol. 2004 Aug;186(16):5480-5.  PMID 15292150

Gene Ontology Term

GO:0009291: unidirectional conjugation (biological_process)

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
TraF pilus assembly protein	TraF	YES	TIGR02739 (HMM): type-F conjugative transfer system pilin assembly protein TraF	GO:0009291: unidirectional conjugation
Possible alternate TraF or TrbB	TraF-lik	NO	TIGR02740 (HMM): TraF-like protein	GO:0009291: unidirectional conjugation
TraH pilus assembly protein	TraH	YES	PF06122 (HMM): conjugative relaxosome accessory transposon protein	GO:0009291: unidirectional conjugation
TraI plasmid relaxase/helicase protein	TraI	YES	TIGR02760 (HMM): conjugative transfer relaxase protein TraI	GO:0009291: unidirectional conjugation
TraN outer membrane mating-pair stabilization protein	TraN	YES	PF06986 (HMM): mating pair stabilisation protein TraN TIGR02750 (HMM): type-F conjugative transfer system mating-pair stabilization protein TraN	GO:0009291: unidirectional conjugation GO:0009291: unidirectional conjugation
TraQ pilin inner membrane chaperone	TraQ	NO	TIGR02741 (HMM): type-F conjugative transfer system pilin chaperone TraQ	GO:0009291: unidirectional conjugation
TraU mating-pair stabilization protein	TraU	YES	PF06834 (HMM): TraU protein	GO:0009291: unidirectional conjugation
TraW pilus assembly protein	TraW	YES	TIGR02743 (HMM): type-F conjugative transfer system protein TraW	GO:0009291: unidirectional conjugation
TraX pilin acetylase	TraX	NO	TIGR02755 (HMM): type-F conjugative transfer system pilin acetylase TraX	GO:0009291: unidirectional conjugation
TrbB pilus assembly disulfide isomerase	TrbB	YES	TIGR02738 (HMM): type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB	GO:0009291: unidirectional conjugation
possible alternate TrbB, CXXC-containing protein	TrbB-lik	NO	CLUST+CXXCmotif (MANUAL)
TrbC pilus assembly protein	TrbC	YES	TIGR02742 (HMM): type-F conjugative transfer system pilin assembly protein TrbC	GO:0009291: unidirectional conjugation
TrbI pilus assembly protein	TrbI	NO	TIGR02744 (HMM): type-F conjugative transfer system protein TrbI	GO:0009291: unidirectional conjugation

Parent Properties

Accession	Name
GenProp0489	F-type conjugation system

Sibling Properties

Accession	Name
GenProp0485	F and P-type conjugation systems (type IV secretion), common components