Genome Property Definition Page

AccessionGenProp0641
Namespermidine biosynthesis from putrescine and S-adenosylmethionine
TypePATHWAY
DescriptionSpermine, spermidine and putrescine are a family of polyamines (positively charged organic polycations) that are important for cellular growth, most likely by stabilizing polynucleotides and membranes. Spermidine is derived from putrescine and the 4-aminobutyrate moiety of methionine (indirectly via S-adenosyl methionine). Spermine is synthesized by a second addition of 4-aminobutyrate to spermidine, and is more commonly found in eukaryotes.
JCVI RolePolyamine biosynthesis
Parent PropertyGenProp0063: biosynthesis
GenProp0063: biosynthesis
GenProp0063: biosynthesis

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
S-adenosylmethionine decarboxylasespeDYESPF02675 (HMM): S-adenosylmethionine decarboxylase
S-adenosylmethionine decarboxylasespeDYESPF02675 (HMM): S-adenosylmethionine decarboxylase
S-adenosylmethionine decarboxylasespeDYESPF02675 (HMM): S-adenosylmethionine decarboxylase
spermidine synthasespeEYESTIGR00417 (HMM): spermidine synthase
spermidine synthasespeEYESTIGR00417 (HMM): spermidine synthase
spermidine synthasespeEYESTIGR00417 (HMM): spermidine synthase

Parent Properties
AccessionName
GenProp0063biosynthesis
GenProp0063biosynthesis
GenProp0063biosynthesis


Sibling Properties
AccessionName
GenProp0077natural products biosynthesis
GenProp0126amino acid biosynthesis
GenProp0184cofactor biosynthesis
GenProp0185nucleotide biosynthesis
GenProp0186storage and structural polymer biosynthesis
GenProp0197protein biosynthesis
GenProp0219spermidine biosynthesis from arginine (via agmatine)
GenProp0267osmolyte biosynthesis
GenProp0642putrescine biosynthesis from arginine utilizing agmatinase
GenProp0643putrescine biosynthesis from arginine via ornithine
GenProp0644putrescine biosynthesis from glutamate via ornithine
GenProp0645putrescine biosynthesis
GenProp0724phosphonoacetaldehyde biosynthesis from phosphoenolpyruvate
GenProp0738agmatine to putrescine via N-carbamoylputrescine
GenProp0795carbohydrate biosynthesis
GenProp0838lipid biosynthesis
GenProp0909capreomycidine biosynthesis
GenProp0942alkane biosynthesis, cyanobacterial
GenProp1053rSAM/selenodomain system
GenProp1056rhizo-twelve system
GenProp1057radical SAM/SPASM system GeoRSP