Genome Property Definition Page

AccessionGenProp0655
Nameexopolysaccharide biosynthesis, exosortase B-associated
TypeSYSTEM
DescriptionAt least 30 different bacterial species known so far have the PEP-CTERM/exosortase system believed to process proteins analogously to the LPXTG/sortase system. Genes associated with this processing are found among exopolysaccharide biosynthesis genes, suggesting that PEP-CTERM proteins are part of this exopolysaccharide system, and therefore are likely to be transported across the outer membrane. This property represents a panel of exopolysaccharide biosynthesis genes where each belongs to a subfamily that marks its host gene as carrying the PEP-CTERM/exopolysaccharide system. This type 2 version of the system is found in Methylobacillus sp. strain 12S where it is embedded in a region for the biosynthesis of the exopolysaccharide mthanolan.
Parent PropertyGenProp0186: storage and structural polymer biosynthesis
GenProp1048: quorum-sensing, biofilm formation, and developmental systems
GenProp0186: storage and structural polymer biosynthesis
GenProp1048: quorum-sensing, biofilm formation, and developmental systems
GenProp0186: storage and structural polymer biosynthesis
GenProp1048: quorum-sensing, biofilm formation, and developmental systems
Literature References
[ 1 ]Yoshida T, Ayabe Y, Yasunaga M, Usami Y, Habe H, Nojiri H, Omori T  Genes involved in the synthesis of the exopolysaccharide methanolan by the obligate methylotroph Methylobacillus sp strain 12S.  Microbiology. 2003 Feb;149(Pt 2):431-44.  PMID 12624205
[ 2 ]Haft DH, Paulsen IT, Ward N, Selengut JD  Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic.  BMC Biol. 2006 Aug 24;4(1):29.  PMID 16930487
[ 1 ]Yoshida T, Ayabe Y, Yasunaga M, Usami Y, Habe H, Nojiri H, Omori T  Genes involved in the synthesis of the exopolysaccharide methanolan by the obligate methylotroph Methylobacillus sp strain 12S.  Microbiology. 2003 Feb;149(Pt 2):431-44.  PMID 12624205
[ 2 ]Haft DH, Paulsen IT, Ward N, Selengut JD  Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic.  BMC Biol. 2006 Aug 24;4(1):29.  PMID 16930487
[ 1 ]Yoshida T, Ayabe Y, Yasunaga M, Usami Y, Habe H, Nojiri H, Omori T  Genes involved in the synthesis of the exopolysaccharide methanolan by the obligate methylotroph Methylobacillus sp strain 12S.  Microbiology. 2003 Feb;149(Pt 2):431-44.  PMID 12624205
[ 2 ]Haft DH, Paulsen IT, Ward N, Selengut JD  Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic.  BMC Biol. 2006 Aug 24;4(1):29.  PMID 16930487

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
Transcriptional regulator EpsAEpsANOTIGR03020 (HMM): transcriptional regulator EpsA
TIGR03020 (HMM): transcriptional regulator EpsA
Transcriptional regulator EpsAEpsANOTIGR03020 (HMM): transcriptional regulator EpsA
TIGR03020 (HMM): transcriptional regulator EpsA
Transcriptional regulator EpsAEpsANOTIGR03020 (HMM): transcriptional regulator EpsA
TIGR03020 (HMM): transcriptional regulator EpsA
Undecaprenyl-phosphate glucose phosphotransferase EpsBEpsBYESTIGR03023 (HMM-CLUST): undecaprenyl-phosphate glucose phosphotransferase
TIGR03023 (HMM-CLUST): undecaprenyl-phosphate glucose phosphotransferase
Undecaprenyl-phosphate glucose phosphotransferase EpsBEpsBYESTIGR03023 (HMM-CLUST): undecaprenyl-phosphate glucose phosphotransferase
TIGR03023 (HMM-CLUST): undecaprenyl-phosphate glucose phosphotransferase
Undecaprenyl-phosphate glucose phosphotransferase EpsBEpsBYESTIGR03023 (HMM-CLUST): undecaprenyl-phosphate glucose phosphotransferase
TIGR03023 (HMM-CLUST): undecaprenyl-phosphate glucose phosphotransferase
polysaccharide export proteinEpsEYESTIGR03028 (HMM): polysaccharide export protein EpsE
TIGR03028 (HMM): polysaccharide export protein EpsE
polysaccharide export proteinEpsEYESTIGR03028 (HMM): polysaccharide export protein EpsE
TIGR03028 (HMM): polysaccharide export protein EpsE
polysaccharide export proteinEpsEYESTIGR03028 (HMM): polysaccharide export protein EpsE
TIGR03028 (HMM): polysaccharide export protein EpsE
chain length determinant protein EpsFEpsFYESTIGR03017 (HMM): chain length determinant protein EpsF
TIGR03017 (HMM): chain length determinant protein EpsF
chain length determinant protein EpsFEpsFYESTIGR03017 (HMM): chain length determinant protein EpsF
TIGR03017 (HMM): chain length determinant protein EpsF
chain length determinant protein EpsFEpsFYESTIGR03017 (HMM): chain length determinant protein EpsF
TIGR03017 (HMM): chain length determinant protein EpsF
protein tyrosine kinase EpsGEpsGYESTIGR03029 (HMM): chain length determinant protein tyrosine kinase EpsG
TIGR03029 (HMM): chain length determinant protein tyrosine kinase EpsG
protein tyrosine kinase EpsGEpsGYESTIGR03029 (HMM): chain length determinant protein tyrosine kinase EpsG
TIGR03029 (HMM): chain length determinant protein tyrosine kinase EpsG
protein tyrosine kinase EpsGEpsGYESTIGR03029 (HMM): chain length determinant protein tyrosine kinase EpsG
TIGR03029 (HMM): chain length determinant protein tyrosine kinase EpsG
exosortase 2EpsH-2YESTIGR03113 (HMM): exosortase B
TIGR03113 (HMM): exosortase B
exosortase 2EpsH-2YESTIGR03113 (HMM): exosortase B
TIGR03113 (HMM): exosortase B
exosortase 2EpsH-2YESTIGR03113 (HMM): exosortase B
TIGR03113 (HMM): exosortase B
EpsL proteinEpsLYESTIGR03014 (HMM): exopolysaccharide biosynthesis operon protein EpsL
TIGR03014 (HMM): exopolysaccharide biosynthesis operon protein EpsL
EpsL proteinEpsLYESTIGR03014 (HMM): exopolysaccharide biosynthesis operon protein EpsL
TIGR03014 (HMM): exopolysaccharide biosynthesis operon protein EpsL
EpsL proteinEpsLYESTIGR03014 (HMM): exopolysaccharide biosynthesis operon protein EpsL
TIGR03014 (HMM): exopolysaccharide biosynthesis operon protein EpsL

Parent Properties
AccessionName
GenProp0186storage and structural polymer biosynthesis
GenProp1048quorum-sensing, biofilm formation, and developmental systems
GenProp0186storage and structural polymer biosynthesis
GenProp1048quorum-sensing, biofilm formation, and developmental systems
GenProp0186storage and structural polymer biosynthesis
GenProp1048quorum-sensing, biofilm formation, and developmental systems


Sibling Properties
AccessionName
GenProp0055polyhydroxyalkanoic acids
GenProp0156cyanophycin-like storage polymers
GenProp0158peptidoglycan(murein) biosynthesis
GenProp0168glycogen system
GenProp0183dTDP-L-rhamnose biosynthesis from dTDP-4-dehydro-L-rhamnose
GenProp0297lipopolysaccharide biosynthesis
GenProp0652exopolysaccharide biosynthesis, exosortase A-associated
GenProp0658cellulose biosynthesis
GenProp0793CMP-N-acetylneuraminate biosynthesis from UDP-N-acetylglucosamine
GenProp0822poly(gamma-glutamic acid) biosynthesis
GenProp0906poly-beta-1,6 N-acetyl-D-glucosamine system, IcaADBC type
GenProp0907poly-beta-1,6 N-acetyl-D-glucosamine system, PgaABCD type
GenProp0757quorum-sensing, autoinducer-2 system
GenProp0849quorum-sensing, Bacillus PlcR-PapR system
GenProp1011quorum-sensing system, cyclic peptide-mediated