Genome Property Definition Page

AccessionGenProp0664
Nameprotein sorting system, sortase type, SrtB class
TypeSYSTEM
DescriptionThis is a family of sortases and their substrates, less abundant than the housekeeping sortase, SrtA, and the LPXTG-like target sequences. SrtB is Listeria monocytogenes appears to process two classes of signal, NXZTN and NPKXZ (see PMID:16247833). Note that the protein called SrtB in Streptococcus pyogenes (see PMID:11914350) is a member of the SrtA family, not the family described here, while the protein called SrtC2 is a member of the SrtB family (see PMID:15317792).
JCVI RoleProtein and peptide secretion and trafficking
Parent PropertyGenProp0069: cell surface component
GenProp0179: protein transport
Literature References
[ 1 ]Bierne H, Garandeau C, Pucciarelli MG, Sabet C, Newton S, Garcia-del Portillo F, Cossart P, Charbit A  Sortase B, a new class of sortase in Listeria monocytogenes.  J Bacteriol. 2004 Apr;186(7):1972-82.  PMID 15028680
[ 2 ]Barnett TC, Patel AR, Scott JR  A novel sortase, SrtC2, from Streptococcus pyogenes anchors a surface protein containing a QVPTGV motif to the cell wall.  J Bacteriol. 2004 Sep;186(17):5865-75.  PMID 15317792

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
sortase, SrtB familySrtBYESPF07170 (HMM):
TIGR03064 (HMM): sortase, SrtB family
sortase B target sequencetargetYESTIGR03063 (HMM): sortase B cell surface sorting signal
TIGR03065 (HMM): sortase B signal domain, QVPTGV class
TIGR03068 (HMM): sortase B signal domain, NPQTN class

Parent Properties
AccessionName
GenProp0069cell surface component
GenProp0179protein transport


Sibling Properties
AccessionName
GenProp0007flagella
GenProp0012outer membrane
GenProp0022S-layer
GenProp0056type IV pilus
GenProp0062capsule
GenProp0158peptidoglycan(murein) biosynthesis
GenProp0297lipopolysaccharide biosynthesis
GenProp0326protein sorting system, PEP-CTERM/exosortase (generic)
GenProp0626protein sorting system, sortase type, LPXTG/SrtA class
GenProp0725outer membrane protein assembly complex
GenProp0811S-layer homology domain-mediated cell wall binding
GenProp0847exosporium
GenProp0857anchored repeat-class ABC transporter, P. acnes type
GenProp0859protein sorting system, proteobacterial dedicated sortase type
GenProp0052type III secretion
GenProp0053type II secretion
GenProp0054type IV secretion
GenProp0059type I secretion
GenProp0127Tat (Sec-independent) protein export
GenProp0205signal recognition system, bacterial
GenProp0207lipoprotein localization system lolABCDE
GenProp0209Sec system preprotein translocase
GenProp0295prokaryotic N-terminal cleavage/methylation, type IV pilin-like
GenProp0669protein sorting system, putative, exosortase G class
GenProp0735type VI secretion
GenProp0778protein sorting system, GlyGly-CTERM/rhombosortase
GenProp0844accessory Sec system for serine-rich glycoprotein transport
GenProp0845protein sorting system, KxYKxGKxW class
GenProp0904type VII secretion, Actinobacteria form
GenProp0905type VII secretion, Firmicutes form
GenProp0928OMP chaperone system: SurA-Skp-DegP
GenProp0957protein sorting system, SipW class
GenProp0978protein sorting system, PGF-CTERM/archaeosortase A
GenProp0979protein sorting system, PEF-CTERM/archaeosortase C
GenProp0980protein sorting system, putative, exosortase F class
GenProp0983protein sorting system, VPXXXP-CTERM/archaeosortase B
GenProp0985protein sorting system, VPDSG-CTERM/exosortase C
GenProp0986protein sorting system, VPLPA-CTERM/exosortase D
GenProp0987protein sorting system, cyano-PEP-CTERM class
GenProp0989protein sorting system, VPEID-CTERM/exosortase E
GenProp0993protein sorting system, PIP-CTERM/archaeosortase D
GenProp0996protein sorting system, IPTLxxWG-CTERM/exosortase H
GenProp0999Por secretion system
GenProp1005protein sorting system, putative, exosortase J class
GenProp1054protein sorting system, MSEP-CTERM/exosortase K
GenProp1055protein sorting system, PEFG-CTERM/thaumarchaeosortase
GenProp1074type V secretion