Genome Property Definition Page

Namec-type cytochrome biogenesis, system I
DescriptionAssembling c-type cytochromes outside the bacterial inner membrane requires apocytochome export, heme export, heme ligation, and chaperones for both heme and apocytochromes, Of three different c-type cytochrome biogenesis systems, this is system I. It features the operon ccmABCDEFGHI in Escherichia coli and the equivalent genes in many other bacterial species.
JCVI RoleElectron transport
Parent PropertyGenProp0167: cellular growth, organization and division
Literature References
[ 1 ]Ahuja U, Thony-Meyer L  CcmD is involved in complex formation between CcmC and the heme chaperone CcmE during cytochrome c maturation.  J Biol Chem. 2005 Jan 7;280(1):236-43. Epub 2004 Oct 28.  PMID 15513913

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
heme ABC exporter, ATP-binding protein CcmACcmAYESTIGR01189 (HMM): heme ABC exporter, ATP-binding protein CcmA
heme exporter protein CcmBCcmBYESTIGR01190 (HMM): heme exporter protein CcmB
heme exporter protein CcmCCcmCYESTIGR01191 (HMM): heme exporter protein CcmC
heme exporter protein CcmDCcmDYESPF04995 (HMM): heme exporter protein D
TIGR04391 (HMM-CLUST): CcmD family protein
cytochrome c-type biogenesis protein CcmECcmEYESPF03100 (HMM): cytochrome c-type biogenesis protein CcmE
cytochrome c-type biogenesis protein CcmFCcmFYESTIGR00353 (HMM): cytochrome c-type biogenesis protein CcmF
CcmG proteinCcmGYESTIGR00385 (HMM): periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily
cytochrome C biogenesis protein CcmH/CycL/NrfF/Ccl2CcmHYESPF03918 (HMM): cytochrome c biogenesis protein
cytochrome c-type biogenesis protein CcmICcmINOTIGR03142 (HMM): cytochrome c-type biogenesis protein CcmI

Parent Properties
GenProp0167cellular growth, organization and division

Sibling Properties
GenProp0049spore formation
GenProp0165minCDE system
GenProp0166mreBCD system
GenProp0173cell shape
GenProp0201SMC-ScpA-ScpB complex
GenProp0206bacterial cell division septum system
GenProp0296intracytoplasmic membranes
GenProp0460gas vesicle
GenProp0680c-type cytochrome biogenesis, system II