Genome Property Definition Page

Accession

GenProp0684

Name

FtsH/HflKC protease complex

Type

SYSTEM

JCVI Role

Degradation of proteins, peptides, and glycopeptides

Parent Property

GenProp0301: protein degradation

Literature References

[ 1 ]Kihara A, Akiyama Y, Ito K Different pathways for protein degradation by the FtsH/HflKC membrane-embedded protease complex: an implication from the interference by a mutant form of a new substrate protein, YccA. J Mol Biol. 1998 May 29;279(1):175-88. PMID 9636708

Components

Step Name	Step Num	Required	Evidence (Method)
ATP-dependent metallopeptidase FtsH (HflB)	HflB	YES	TIGR01241 (HMM): ATP-dependent metallopeptidase HflB
HflC protein	HflC	YES	TIGR01932 (HMM): HflC protein
HflK protein	HflK	YES	TIGR01933 (HMM): HflK protein

Parent Properties

Accession	Name
GenProp0301	protein degradation

Sibling Properties

Accession	Name
GenProp0211	tmRNA trans-translation system
GenProp0251	clpXP degradation machine
GenProp0833	proteasome-targeting modification by pupylation
GenProp0834	proteasome, bacterial
GenProp0835	ATP-dependent protease HslVU