Genome Property Definition Page

AccessionGenProp0704
NametRNA U34 carboxymethylaminomethyl modification
TypePATHWAY
DescriptionGidA and MnmE act as a heterotetramer for the cmnmU34 modification in bacteria and eukarya. They are absent from the Archaea. Their action may be followed by that of the bifunctional MnmC (YfcK) protein.
JCVI RoletRNA and rRNA base modification
Parent PropertyGenProp0197: protein biosynthesis
GenProp0819: RNA metabolism

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
U34 modification protein GidAGidAYESTIGR00136 (HMM): tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA
cysteine desulfurase IscSIscSYESTIGR02006 (HMM): cysteine desulfurase IscS
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferaseMnmAYESTIGR00420 (HMM): tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase
MnmC, C-term modelMnmC_CNOTIGR03197 (HMM): tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain
U34 modification protein MnmEMnmEYESTIGR00450 (HMM): tRNA modification GTPase TrmE

Parent Properties
AccessionName
GenProp0197protein biosynthesis
GenProp0819RNA metabolism


Sibling Properties
AccessionName
GenProp0016selenocysteine system
GenProp0312pyrrolysine
GenProp0132transcription termination - antitermination Nus factors
GenProp0148release factor 2 programmed frameshift
GenProp0174ribosome, bacterial, large subunit
GenProp0175ribosome, bacterial, small subunit
GenProp0188GatABC aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase complex
GenProp0189tRNA-Gln direct aminoacylation
GenProp0211tmRNA trans-translation system
GenProp0258tRNA aminoacylation
GenProp0259tRNA-Asn direct aminoacylation
GenProp0304cysteine biosynthesis, tRNA-dependent
GenProp0634Sigma-54 (RpoN) systems
GenProp0692selenouridine-containing tRNA
GenProp0740translation initiation, bacterial
GenProp0741translation elongation, bacterial
GenProp0746translation termination, bacterial
GenProp0812rho-dependent termination
GenProp0262RNA polymerase, bacterial
GenProp04826S RNA (eubacterial RNA polymerase regulator)
GenProp0677queuosine (Q-tRNA) biosynthesis from preQ0
GenProp0898RNA ligase/unknown protein pair
GenProp0948RNA repair, Hen1/Pnkp system
GenProp1060tRNA N6-threonylcarbamoyladenosine modification
GenProp1077tRNA(Pro) cmo5UGG modification
GenProp108216S rRNA C1402 m(4)Cm modification