Genome Property Definition Page

AccessionGenProp0707
Namebotulinum toxin system
TypeSYSTEM
DescriptionClostridium botulinum contains a virulence cassette encoding a potent neurotoxin called BoNT. Also found in this operon are several hemagglutinin proteins and a regulatory sigma-70 gene.
JCVI RolePathogenesis
Parent PropertyGenProp0074: virulence
GenProp0074: virulence
GenProp0074: virulence

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
neurotoxin componentBoNTYESPF07951 (HMM): Clostridium neurotoxin, C-terminal receptor binding
PF07952 (HMM): Clostridium neurotoxin, Translocation domain
PF07951 (HMM): Clostridium neurotoxin, C-terminal receptor binding
PF07952 (HMM): Clostridium neurotoxin, Translocation domain
neurotoxin componentBoNTYESPF07951 (HMM): Clostridium neurotoxin, C-terminal receptor binding
PF07952 (HMM): Clostridium neurotoxin, Translocation domain
PF07951 (HMM): Clostridium neurotoxin, C-terminal receptor binding
PF07952 (HMM): Clostridium neurotoxin, Translocation domain
neurotoxin componentBoNTYESPF07951 (HMM): Clostridium neurotoxin, C-terminal receptor binding
PF07952 (HMM): Clostridium neurotoxin, Translocation domain
PF07951 (HMM): Clostridium neurotoxin, C-terminal receptor binding
PF07952 (HMM): Clostridium neurotoxin, Translocation domain
Sigma-70 factor regulatorBotRYESTIGR03209 (HMM): transcriptional regulator BotR, P-21
TIGR03209 (HMM): transcriptional regulator BotR, P-21
Sigma-70 factor regulatorBotRYESTIGR03209 (HMM): transcriptional regulator BotR, P-21
TIGR03209 (HMM): transcriptional regulator BotR, P-21
Sigma-70 factor regulatorBotRYESTIGR03209 (HMM): transcriptional regulator BotR, P-21
TIGR03209 (HMM): transcriptional regulator BotR, P-21
haemagglutinin HA17HA-17YESPF05588 (HMM): Clostridium botulinum HA-17 protein
PF05588 (HMM): Clostridium botulinum HA-17 protein
haemagglutinin HA17HA-17YESPF05588 (HMM): Clostridium botulinum HA-17 protein
PF05588 (HMM): Clostridium botulinum HA-17 protein
haemagglutinin HA17HA-17YESPF05588 (HMM): Clostridium botulinum HA-17 protein
PF05588 (HMM): Clostridium botulinum HA-17 protein
haemagglutinin HA33HA-33YESPF00652 (HMM): ricin-type beta-trefoil lectin domain
PF00652 (HMM): ricin-type beta-trefoil lectin domain
haemagglutinin HA33HA-33YESPF00652 (HMM): ricin-type beta-trefoil lectin domain
PF00652 (HMM): ricin-type beta-trefoil lectin domain
haemagglutinin HA33HA-33YESPF00652 (HMM): ricin-type beta-trefoil lectin domain
PF00652 (HMM): ricin-type beta-trefoil lectin domain
haemagglutinin HA70HA-70YESPF03505 (HMM): Clostridium enterotoxin
PF03505 (HMM): Clostridium enterotoxin
haemagglutinin HA70HA-70YESPF03505 (HMM): Clostridium enterotoxin
PF03505 (HMM): Clostridium enterotoxin
haemagglutinin HA70HA-70YESPF03505 (HMM): Clostridium enterotoxin
PF03505 (HMM): Clostridium enterotoxin
non-toxin, non-haemaglutinin componentntnhYESPF08470 (HMM): nontoxic nonhaemagglutinin C-terminal
PF08470 (HMM): nontoxic nonhaemagglutinin C-terminal
non-toxin, non-haemaglutinin componentntnhYESPF08470 (HMM): nontoxic nonhaemagglutinin C-terminal
PF08470 (HMM): nontoxic nonhaemagglutinin C-terminal
non-toxin, non-haemaglutinin componentntnhYESPF08470 (HMM): nontoxic nonhaemagglutinin C-terminal
PF08470 (HMM): nontoxic nonhaemagglutinin C-terminal

Parent Properties
AccessionName
GenProp0074virulence
GenProp0074virulence
GenProp0074virulence


Sibling Properties
AccessionName
GenProp0032pathogen of plants
GenProp0049spore formation
GenProp0051urease
GenProp0052type III secretion
GenProp0056type IV pilus
GenProp0062capsule
GenProp0154intrinsic pathogen of animals
GenProp0648phage shock protein regulon
GenProp0849quorum-sensing, Bacillus PlcR-PapR system