Genome Property Definition Page

AccessionGenProp0708
Namecatechol meta-cleavage pathway
TypePATHWAY
DescriptionThe metabolism of many aromatic compounds proceeds by way of catechol, a compound chemically similar to benzene except that a pair of adjacent H atoms of benzene are replaced by OH groups of catechol. This property describes the meta-cleavage pathway, in which catechol 2,3-dioxygenase cleaves the ring at the meta position. Degradation continues to pyruvate and acetyl-CoA. Some compounds degraded by way of catechol and this pathway include benzoate, toluene, salicylate, phenol, napthalene, and 3,4-dimethylphenol (dmp).
JCVI RoleOther
Parent PropertyGenProp0142: catabolism

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
catechol 2,3-dioxygenase1_dmpBYESTIGR03211 (HMM): catechol 2,3 dioxygenase
2-hydroxymuconic semialdehyde hydrolase234dmpDYES
2-hydroxymuconic semialdehyde dehydrogenase2_dmpCYESTIGR03216 (HMM): 2-hydroxymuconic semialdehyde dehydrogenase
4-oxalocrotonate isomerase3_dmpIYESTIGR00013 (HMM): 4-oxalocrotonate tautomerase family enzyme
4-oxalocrotonate decarboxylase4_dmpHYESTIGR03218 (HMM): 4-oxalocrotonate decarboxylase
2-oxopent-4-enoate hydratase5_dmpEYESTIGR03220 (HMM): 2-oxopent-4-enoate hydratase
2-oxo-4-hydroxypentanoate aldolase6_dmpGYESTIGR03217 (HMM): 4-hydroxy-2-oxovalerate aldolase
acetaldehyde dehydrogenase (acetylating)7_dmpFYESTIGR03215 (HMM): acetaldehyde dehydrogenase (acetylating)

Parent Properties
AccessionName
GenProp0142catabolism


Sibling Properties
AccessionName
GenProp0055polyhydroxyalkanoic acids
GenProp0141galactose-6-phosphate degradation via tagatose-6-phosphate
GenProp0156cyanophycin-like storage polymers
GenProp0168glycogen system
GenProp0210phenylacetic acid catabolism
GenProp02314-hydroxyphenylacetate degradation
GenProp0233GABA utilization
GenProp02382-aminoethylphosphonate catabolism to acetaldehyde
GenProp0239propionyl-CoA catabolism
GenProp0241phosphonate catabolism
GenProp0271trehalose utilization
GenProp0272pyruvate fermentation to acetoin
GenProp0273protocatechuate degradation to beta-ketoadipate
GenProp0283beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA
GenProp0294ethanolamine catabolism to acetaldehyde
GenProp0457rhamnose catabolism
GenProp0458fucose catabolism
GenProp0461utilization of deoxynucleosides
GenProp0653ectoine catabolism
GenProp0674malonate decarboxylase
GenProp0686allantoin catabolism to glyoxalate and urea
GenProp0687allantoin catabolism to oxamate and carbamoyl-phosphate
GenProp0688urate catabolism to allantoin
GenProp0691glycolysis
GenProp0693fructose utilization as fructose-1,6-bisphosphate
GenProp0694glucose utilization as fructose-1,6-bisphosphate
GenProp0700purine catabolism via urate, xanthine and allantoin
GenProp0702benzoyl-CoA reductase
GenProp07034-hydroxybenzoyl-CoA reductase
GenProp0706cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway
GenProp0709benzoate catabolism BoxABC pathway
GenProp0711catechol ortho-cleavage upper pathway
GenProp0714galactarate utilization via tartronate semi-aldehyde
GenProp0715galactarate utilization via 2-oxoglutarate semialdehyde
GenProp0716glucarate utilization via tartronate semi-aldehyde
GenProp0717glucarate utilization via 2-oxoglutarate semialdehyde
GenProp0718oxalate degradation
GenProp0734amino acid catabolism
GenProp0749choline sulfate utilization
GenProp0760putrescine degradation to GABA via gamma-glutamylation
GenProp0763nicotinate fermentation to pyruvate and propionate
GenProp0813pyrimidine utilization operon, RutABCDEFGR
GenProp0902quinohemoprotein amine dehydrogenase
GenProp1071myo-inositol catabolism
GenProp1072cyanase system
GenProp1076choline TMA-lyase system