Genome Property Definition Page

AccessionGenProp0716
Nameglucarate utilization via tartronate semi-aldehyde
TypeSYSTEM
DescriptionD-glucarate may be utilized by this pathway involving the lyase (aldolase) GarL which produces pyruvate and tartronate semi-aldehyde which may then be furter converted to 3-phosphoglycerate. GarD, the dehydratase and GarR, the reductase, may be present in the absence of GarL and where each is part of different processes. When this can be convincingly demonstrated, this property may be manually annotated as NO.
Parent PropertyGenProp0142: catabolism
Literature References
[ 1 ]Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA  Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli.  Biochemistry. 1998 Oct 13;37(41):14369-75.  PMID 9772162
Gene Ontology TermGO:0019394: glucarate catabolic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
glycerate kinase (2.7.1.31)GarKNOTIGR00045 (HMM-CLUST): glycerate kinase
TIGR00045 (HMM): glycerate kinase
GO:0019394: glucarate catabolic process
GO:0019394: glucarate catabolic process
5-dehydro-4-deoxy-D-glucarate lyase (4.1.2.20)GarLYESTIGR03239 (HMM): 2-dehydro-3-deoxyglucarate aldolaseGO:0019394: glucarate catabolic process
tartronate semialdehyde reductase (1.1.1.60)GarRYESTIGR01505 (HMM): 2-hydroxy-3-oxopropionate reductaseGO:0019394: glucarate catabolic process
glucarate dehydratase (4.2.1.40)GudDYESTIGR03247 (HMM): glucarate dehydrataseGO:0019394: glucarate catabolic process
D-glucarate transporter, putativetranspNOTIGR00893 (HMM-CLUST): D-galactonate transporterGO:0019394: glucarate catabolic process

Parent Properties
AccessionName
GenProp0142catabolism


Sibling Properties
AccessionName
GenProp0055polyhydroxyalkanoic acids
GenProp0141galactose-6-phosphate degradation via tagatose-6-phosphate
GenProp0156cyanophycin-like storage polymers
GenProp0168glycogen system
GenProp0210phenylacetic acid catabolism
GenProp02314-hydroxyphenylacetate degradation
GenProp0233GABA utilization
GenProp02382-aminoethylphosphonate catabolism to acetaldehyde
GenProp0239propionyl-CoA catabolism
GenProp0241phosphonate catabolism
GenProp0271trehalose utilization
GenProp0272pyruvate fermentation to acetoin
GenProp0273protocatechuate degradation to beta-ketoadipate
GenProp0283beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA
GenProp0294ethanolamine catabolism to acetaldehyde
GenProp0457rhamnose catabolism
GenProp0458fucose catabolism
GenProp0461utilization of deoxynucleosides
GenProp0653ectoine catabolism
GenProp0674malonate decarboxylase
GenProp0686allantoin catabolism to glyoxalate and urea
GenProp0687allantoin catabolism to oxamate and carbamoyl-phosphate
GenProp0688urate catabolism to allantoin
GenProp0691glycolysis
GenProp0693fructose utilization as fructose-1,6-bisphosphate
GenProp0694glucose utilization as fructose-1,6-bisphosphate
GenProp0700purine catabolism via urate, xanthine and allantoin
GenProp0702benzoyl-CoA reductase
GenProp07034-hydroxybenzoyl-CoA reductase
GenProp0706cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway
GenProp0708catechol meta-cleavage pathway
GenProp0709benzoate catabolism BoxABC pathway
GenProp0711catechol ortho-cleavage upper pathway
GenProp0714galactarate utilization via tartronate semi-aldehyde
GenProp0715galactarate utilization via 2-oxoglutarate semialdehyde
GenProp0717glucarate utilization via 2-oxoglutarate semialdehyde
GenProp0718oxalate degradation
GenProp0734amino acid catabolism
GenProp0749choline sulfate utilization
GenProp0760putrescine degradation to GABA via gamma-glutamylation
GenProp0763nicotinate fermentation to pyruvate and propionate
GenProp0813pyrimidine utilization operon, RutABCDEFGR
GenProp0902quinohemoprotein amine dehydrogenase
GenProp1071myo-inositol catabolism
GenProp1072cyanase system
GenProp1076choline TMA-lyase system