Genome Property Definition Page

AccessionGenProp0719
Namemethyl-coenzyme M reductase
TypeSYSTEM
DescriptionMethyl-coenzyme M reductase is a nickel-containing, alpha2/beta2/gamma2 hexameric enzyme that catalyzes the final step in methanogenesis. This enzyme has several novel post-translational modifications; it is found in methanogenic archaea, many of which are hyperthermophiles. Many archaea have two versions of this enzyme. It appears that some Archaea are methanotrophic; homologous proteins act in the anaerobic oxidation of methane rather than in methanogenesis.
JCVI RoleMethanogenesis
Parent PropertyGenProp0011: methanogenesis
GenProp0031: methane utilization
GenProp0011: methanogenesis
GenProp0031: methane utilization
GenProp0011: methanogenesis
GenProp0031: methane utilization

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
methyl-coenzyme M reductase, alpha subunitalphaYESTIGR03256 (HMM): methyl-coenzyme M reductase, alpha subunit
methyl-coenzyme M reductase, alpha subunitalphaYESTIGR03256 (HMM): methyl-coenzyme M reductase, alpha subunit
methyl-coenzyme M reductase, alpha subunitalphaYESTIGR03256 (HMM): methyl-coenzyme M reductase, alpha subunit
methyl-coenzyme M reductase, beta subunitbetaYESTIGR03257 (HMM): methyl-coenzyme M reductase, beta subunit
methyl-coenzyme M reductase, beta subunitbetaYESTIGR03257 (HMM): methyl-coenzyme M reductase, beta subunit
methyl-coenzyme M reductase, beta subunitbetaYESTIGR03257 (HMM): methyl-coenzyme M reductase, beta subunit
methyl-coenzyme M reductase, gamma subunitgammaYESTIGR03259 (HMM): methyl-coenzyme M reductase, gamma subunit
methyl-coenzyme M reductase, gamma subunitgammaYESTIGR03259 (HMM): methyl-coenzyme M reductase, gamma subunit
methyl-coenzyme M reductase, gamma subunitgammaYESTIGR03259 (HMM): methyl-coenzyme M reductase, gamma subunit
methyl coenzyme M reductase system, component A2mcr_A2YESTIGR03269 (HMM): methyl coenzyme M reductase system, component A2
methyl coenzyme M reductase system, component A2mcr_A2YESTIGR03269 (HMM): methyl coenzyme M reductase system, component A2
methyl coenzyme M reductase system, component A2mcr_A2YESTIGR03269 (HMM): methyl coenzyme M reductase system, component A2
methyl-coenzyme M reductase I operon protein Coper_CYESTIGR03264 (HMM): methyl-coenzyme M reductase I operon protein C
methyl-coenzyme M reductase I operon protein Coper_CYESTIGR03264 (HMM): methyl-coenzyme M reductase I operon protein C
methyl-coenzyme M reductase I operon protein Coper_CYESTIGR03264 (HMM): methyl-coenzyme M reductase I operon protein C
methyl-coenzyme M reductase operon protein Doper_DYESTIGR03260 (HMM): methyl-coenzyme M reductase operon protein D
methyl-coenzyme M reductase operon protein Doper_DYESTIGR03260 (HMM): methyl-coenzyme M reductase operon protein D
methyl-coenzyme M reductase operon protein Doper_DYESTIGR03260 (HMM): methyl-coenzyme M reductase operon protein D

Parent Properties
AccessionName
GenProp0011methanogenesis
GenProp0031methane utilization
GenProp0011methanogenesis
GenProp0031methane utilization
GenProp0011methanogenesis
GenProp0031methane utilization


Sibling Properties
AccessionName
GenProp0288tetrahydromethanopterin S-methyltransferase complex
GenProp0722methanogenesis marker set
GenProp0666membrane-associated monooxygenase (methane/ammonia)