Genome Property Definition Page

Name2-aminoethylphosphonate utilization
Description2-aminoethylphosphonate (2-AEP) is a common phosphonate compound found in the environment and at least two related pathways are known for its catabolism. The critical enzyme, PhnW (2-AEP:pyruvate aminotransferase) is found in both of these pathways as well as (working in the opposite direction), biosynthetic pathways. Additionally, two different ABC transporter complexes are likely responsible for the import of 2-AEP.
Parent PropertyGenProp0241: phosphonate catabolism

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
2-aminoethylphosphonate catabolic pathwaysAEPcatYESGenProp0238 (GENPROP): 2-aminoethylphosphonate catabolism to acetaldehyde
GenProp0713 (GENPROP): 2-aminoethylphosphonate catabolism via phosphonoacetate
2-aminoethylphosphonate transport systemsAEPimpYESGenProp0712 (GENPROP): 2-aminoethylphosphonate (AEP) ABC transporter, type I, PhnSTUV
GenProp0721 (GENPROP): 2-aminoethylphosphonate (AEP) ABC transporter, type II
associated FAD-dependent oxidoreductaseoxidoNOTIGR03329 (HMM): putative aminophosphonate oxidoreductase
associated transcriptional regulatorsregulNOTIGR03337 (HMM): phosphonate utilization transcriptional regulator PhnR
TIGR03338 (HMM): phosphonate utilization associated transcriptional regulator
TIGR03339 (HMM): aminoethylphosphonate catabolism associated LysR family transcriptional regulator

Parent Properties
GenProp0241phosphonate catabolism

Child Properties
GenProp02382-aminoethylphosphonate catabolism to acetaldehyde
GenProp07132-aminoethylphosphonate catabolism via phosphonoacetate

Sibling Properties
GenProp0232phosphonates C-P lyase system
GenProp0710generic phosphonates utilization
GenProp07122-aminoethylphosphonate (AEP) ABC transporter, type I, PhnSTUV
GenProp0736proposed phosphonate catabolism pathway HpnWXZ