Genome Property Definition Page
| Accession | GenProp0724 | |
| Name | phosphonoacetaldehyde biosynthesis from phosphoenolpyruvate | |
| Type | PATHWAY | |
| Description | Phosphonacetaldehyde is a precursor of natural products, lipids and polysaccharides containing phosphonates (C-P linkages). Often this is converted by an aminotransferase to the most common naturally occuring phosphonate, 2-aminoethylphosphonate. | |
| JCVI Role | Phosphorus compounds | |
| Parent Property | GenProp0063: biosynthesis GenProp0077: natural products biosynthesis GenProp0242: phosphorus metabolism | |
| Literature References |
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| Gene Ontology Term | GO:0006796: phosphate-containing compound metabolic process (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| PEP phosphomutase | AepX | YES | TIGR02320 (HMM): phosphoenolpyruvate phosphomutase | GO:0006796: phosphate-containing compound metabolic process |
| phosphonopyruvate decarboxylase | AepY | YES | TIGR03297 (HMM): phosphonopyruvate decarboxylase | GO:0006796: phosphate-containing compound metabolic process |
| 2-aminophosphonate transaminase | AepZ | NO | TIGR03301 (SUBFAMILY): 2-aminoethylphosphonate aminotransferase TIGR02326 (SUBFAM-EX): 2-aminoethylphosphonate--pyruvate transaminase | GO:0006796: phosphate-containing compound metabolic process |
| proximal marker of exopolysaccharide biosynthesis | EPS | NO | PF01943 (HMM-CLUST): polysaccharide biosynthesis protein | |
| proximal marker of lipid biosynthesis | Lipid | NO | PF01066 (HMM-CLUST): CDP-alcohol phosphatidyltransferase | |
| proximal marker of natural products biosynthesis | NatPrd | NO | TIGR01787 (HMM-CLUST): squalene/oxidosqualene cyclases | |
| proximal nucleotidyltransferase domain | nuc-tr | NO | PF01467 (HMM-CLUST): cytidylyltransferase PF00483 (HMM-CLUST): nucleotidyl transferase PF02348 (HMM-CLUST): cytidylyltransferase | |
| proximal oxidoreductases/oxygenases | oxido | NO | PF00465 (HMM-CLUST): alcohol dehydrogenase, iron-containing TIGR03250 (HMM-CLUST): putative phosphonoacetaldehyde dehydrogenase PF03171 (HMM-CLUST): oxidoreductase, 2OG-Fe(II) oxygenase family |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0063 | biosynthesis |
| GenProp0077 | natural products biosynthesis |
| GenProp0242 | phosphorus metabolism |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0077 | natural products biosynthesis |
| GenProp0126 | amino acid biosynthesis |
| GenProp0184 | cofactor biosynthesis |
| GenProp0185 | nucleotide biosynthesis |
| GenProp0186 | storage and structural polymer biosynthesis |
| GenProp0197 | protein biosynthesis |
| GenProp0219 | spermidine biosynthesis from arginine (via agmatine) |
| GenProp0267 | osmolyte biosynthesis |
| GenProp0641 | spermidine biosynthesis from putrescine and S-adenosylmethionine |
| GenProp0642 | putrescine biosynthesis from arginine utilizing agmatinase |
| GenProp0643 | putrescine biosynthesis from arginine via ornithine |
| GenProp0644 | putrescine biosynthesis from glutamate via ornithine |
| GenProp0645 | putrescine biosynthesis |
| GenProp0738 | agmatine to putrescine via N-carbamoylputrescine |
| GenProp0795 | carbohydrate biosynthesis |
| GenProp0838 | lipid biosynthesis |
| GenProp0909 | capreomycidine biosynthesis |
| GenProp0942 | alkane biosynthesis, cyanobacterial |
| GenProp1053 | rSAM/selenodomain system |
| GenProp1056 | rhizo-twelve system |
| GenProp1057 | radical SAM/SPASM system GeoRSP |
| GenProp0014 | polyketide biosynthesis, type I |
| GenProp0015 | polyketide biosynthesis, type II |
| GenProp0040 | thiotemplate type non-ribosomal peptide biosynthesis |
| GenProp0169 | hybrid NRPS-PKS natural pruduct biosynthesis genes |
| GenProp0757 | quorum-sensing, autoinducer-2 system |
| GenProp0758 | lycopene biosynthesis from IPP |
| GenProp0770 | siderophore biosynthesis |
| GenProp0807 | bacteriocin system, heterocycle biosynthesis group |
| GenProp0808 | bacteriocin system, TIGR01847 leader group |
| GenProp0809 | bacteriocin system, lactococcin 972 group |
| GenProp0810 | bacteriocin system, linocin M18 group |
| GenProp0823 | violacein biosynthesis |
| GenProp0825 | bacteriocin system, circular bacteriocin group |
| GenProp0853 | lantibiotic system, gallidermin/epidermin family |
| GenProp0861 | bacteriocin system, NHLP (nif11/nitrile hydratase leader peptide) transport group |
| GenProp0901 | post-ribosomal natural product synthesis system, Burkholderia TOMM-type |
| GenProp0919 | SCIFF/radical SAM Clostridial gene pair |
| GenProp0920 | radical SAM Y_X(10)_GDL system |
| GenProp0921 | radical SAM pair and His-Xaa-Ser repeats peptide |
| GenProp0936 | bacteriocin system, sporulation delay protein group |
| GenProp0945 | radical SAM maturase bacteriocin system, CLI_3235 type |
| GenProp0954 | radical SAM-cylized peptide, Pep1357C family |
| GenProp0955 | modified peptide/radical SAM maturase system, YydFG family |
| GenProp0956 | radical SAM maturase/selenobacteriocin system |
| GenProp0962 | methanobactin biosynthesis, Mb-OB3b family |
| GenProp0967 | radical SAM maturase system, CXXX repeats type |
| GenProp0982 | radical SAM maturase system, FibroRumin system |
| GenProp0984 | radical SAM maturase system, GG-Bacteroidales group |
| GenProp0990 | cobaltopeptin biosynthesis |
| GenProp0991 | ATP-grasp maturase system, microviridin/marinostatin class |
| GenProp1000 | ATP-grasp maturase system, uncharacterized |
| GenProp1002 | grasp-with-spasm peptide maturase system |
| GenProp1003 | cysteine S-glycopeptide biosynthesis, sublancin family |
| GenProp1029 | radical SAM/SPASM system SynChlorMet |
| GenProp1037 | radical SAM/SPASM system GRRM |
| GenProp1052 | geopeptide radical SAM/SPASM maturase system |
| GenProp1062 | radical SAM/SPASM system Clo7bot |
| GenProp1065 | radical SAM/SPASM TIGR04347/TIGR04031 system |
| GenProp1078 | sporulation killing factor system |
| GenProp0190 | phosphate ABC transporter (pstSCAB-phoU) |
| GenProp0241 | phosphonate catabolism |
| GenProp0243 | ATP synthases |