Genome Property Definition Page

AccessionGenProp0750
NameUDP-N-acetylglucosamine biosynthesis from fructose-6-phosphate
TypePATHWAY
DescriptionThis pathway converts fructose-6-phosphate in four steps to activated N-acetylglucosamine. GlmS produces glucosamine-6-phosphate. GlmM isomerizes this product to glucosamine-1-phosphate. GlmU, which is bifunctional, adds an acetyl group from acetyl-CoA, then acts as N-acetylglucosamine-1-phosphate uridylyltransferase. The product, UDP-N-acetyl-D-glucosamine, is then used both for murein biosynthesis and (in species with LPS) for lipopolysaccharide biosynthesis.
JCVI RoleBiosynthesis and degradation of murein sacculus and peptidoglycan
Parent PropertyGenProp0795: carbohydrate biosynthesis
GenProp0795: carbohydrate biosynthesis
GenProp0795: carbohydrate biosynthesis
Literature References
[ 1 ] Mengin-Lecreulx D, van Heijenoort J   Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli.   J Bacteriol. 1993 Oct;175(19):6150-7.  PMID 8407787
[ 1 ] Mengin-Lecreulx D, van Heijenoort J   Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli.   J Bacteriol. 1993 Oct;175(19):6150-7.  PMID 8407787
[ 1 ] Mengin-Lecreulx D, van Heijenoort J   Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli.   J Bacteriol. 1993 Oct;175(19):6150-7.  PMID 8407787

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
phosphoglucosamine mutaseglmMYESTIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
TIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
TIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
phosphoglucosamine mutaseglmMYESTIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
TIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
TIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
phosphoglucosamine mutaseglmMYESTIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
TIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
TIGR01455 (HMM): phosphoglucosamine mutase
TIGR03990 (HMM): phosphoglucosamine mutase
glutamine--fructose-6-phosphate transaminase (isomerizing)glmSYESTIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
TIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
TIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
glutamine--fructose-6-phosphate transaminase (isomerizing)glmSYESTIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
TIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
TIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
glutamine--fructose-6-phosphate transaminase (isomerizing)glmSYESTIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
TIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
TIGR01135 (HMM): glutamine-fructose-6-phosphate transaminase (isomerizing)
glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine diphosphorylaseglmUYESTIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine diphosphorylaseglmUYESTIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine diphosphorylaseglmUYESTIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR01173 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
TIGR03991 (HMM): UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase

Parent Properties
AccessionName
GenProp0795carbohydrate biosynthesis
GenProp0795carbohydrate biosynthesis
GenProp0795carbohydrate biosynthesis


Sibling Properties
AccessionName
GenProp0183dTDP-L-rhamnose biosynthesis from dTDP-4-dehydro-L-rhamnose
GenProp0264glucosylglycerol biosynthesis
GenProp0297lipopolysaccharide biosynthesis
GenProp0766anhydro-N-acetylmuramic acid to N-acetylglucosamine-phosphate
GenProp0793CMP-N-acetylneuraminate biosynthesis from UDP-N-acetylglucosamine
GenProp0794proposed N-acetyl sugar amidation module WbuXYZ
GenProp0796CMP-pseudaminic acid biosynthesis from UDP-N-acetylglucosamine
GenProp0811S-layer homology domain-mediated cell wall binding