Genome Property Definition Page

Namefumarate reductase complex
DescriptionFumarate reductase reversibly converts succinate to fumarate with the concomitant production of FADH2. It consists of four components, a flavoprotein, an iron-sulfur protein, ad two other subunits. It is a component of the reverse TCA carbon fixation pathway as well as certain fermentation pathways. Although reversible, certain enzymes have evolved to prefer one direction over the other, this property captures those which are likely to function in the process of fumarate reduction.
Parent PropertyGenProp0070: energy metabolism

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
flavoprotein subunitFrdAYESTIGR01811 (HMM): succinate dehydrogenase or fumarate reductase, flavoprotein subunit
TIGR01176 (HMM): fumarate reductase, flavoprotein subunit
iron-sulfur protein subunitFrdBYESTIGR00384 (HMM): succinate dehydrogenase and fumarate reductase iron-sulfur protein
subunit CFrdCYESPF02300 (HMM): fumarate reductase subunit C
subunit DFrdDYESPF02313 (HMM): fumarate reductase subunit D

Parent Properties
GenProp0070energy metabolism

Sibling Properties
GenProp0023glyoxylate shunt
GenProp0033TCA cycle
GenProp0120pentose phosphate cycle
GenProp0131electron transport
GenProp0243ATP synthases
GenProp0459D-xylose utilization (conversion to D-xylulose-5-phosphate)
GenProp0468Entner-Doudoroff pathway
GenProp0473arsenite oxidase
GenProp0611aerobic respiration
GenProp0636respiratory nitrate reductase
GenProp0637anaerobic dimethyl sulfoxide reductase
GenProp0638trimethylamine N-oxide reductase system
GenProp0682formate-dependent nitrite reductase, seven-gene type
GenProp0683cytochrome c nitrite reductase NrfHA
GenProp0695cytochrome b558/566
GenProp0723hydrogenase, nickel and F420-dependent
GenProp0737anaerobic glycerol-3-phosphate dehydrogenase complex
GenProp0755pyruvate conversion to propionate, anaerobic, FAD/NAD-regenerating
GenProp0764DMSO reductase family type II enzyme
GenProp08412-oxoacid:ferredoxin oxidoreductase
GenProp0856bacterio-opsin system
GenProp0914hydrogenase, [FeFe]-dependent
GenProp0915hydrogenase, mono-iron type
GenProp1089B12-dependent trimeric diol/glycerol dehydratase