Genome Property Definition Page

Namechemotaxis response-regulator system
DescriptionThis property describes chemotaxis response-regulator systems as typified in Escherichia coli, with the histidine kinase CheA, the response regulator CheY, a phosphatase (CheZ in E. coli), and other proteins (CheB, CheW, and CheR in E. coli). This system also requires chemoreceptors, but these may be different in different species and are not currently included.
JCVI RoleChemotaxis and motility
Parent PropertyGenProp0026: chemotaxis
GenProp0551: regulatory systems
Literature References
[ 1 ] Baker MD, Wolanin PM, Stock JB   Signal transduction in bacterial chemotaxis.   Bioessays. 2006 Jan;28(1):9-22.  PMID 16369945
Web ReferencesBacterial chemotaxis (KEGG)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
chemotaxis histidine kinase CheACheAYES2068 (RULE_BASE)

2632 (RULE_BASE)
chemotaxis methylesterase CheBCheBNOPF01339 (HMM): protein-glutamate methylesterase CheB
chemotaxis protein CheDCheDNOPF03975 (HMM): chemotactic sensory transduction protein CheD
chemotaxis methyltransferase CheRCheRNO2066 (RULE_BASE)

PF01739 (HMM-CLUST): protein-glutamate O-methyltransferase CheR, SAM binding domain
chemotaxis adaptor protein CheWCheWYES2065 (RULE_BASE)

2658 (RULE_BASE)
chemotaxis response regulator CheYCheYYES2067 (RULE_BASE)

2660 (RULE_BASE)
chemotaxis phosphatase CheZCheZYESPF04344 (HMM): chemotaxis phosphatase CheZ
2064 (RULE_BASE)
methyl-accepting chemotaxis proteinMCPYESPF00015 (HMM): methyl-accepting chemotaxis protein signaling domain
CheY-P phosphatases, CheC/FliY/FliN/CheXPpaseNOPF04509 (HMM): CheC-like family
operonic Response Regulator Receiver domain proteinRRRNOPF00072 (HMM-CLUST): response regulator receiver domain

Parent Properties
GenProp0551regulatory systems

Sibling Properties
GenProp0456attenuation system: tryptophanase
GenProp0465circadian clock system KaiABC
GenProp0849quorum-sensing, Bacillus PlcR-PapR system