Genome Property Definition Page
| Accession | GenProp0767 | |
| Name | very short patch repair | |
| Type | SYSTEM | |
| Description | Very short patch (VSP) repair is a repair system that recognizes mismatches caused by deamination of 5-methylcytosine (5meC). Cytosine is modified to 5meC by the product of the dcm gene. Vsr is an endonuclease that creates a nick to allow the repair. In Escherichia coli, the second C of the DNA motif CCWGG (where W is A or T) is methylated; deamination yields T:G mispairs reccognized by the vsr gene product. The vsr gene typically is found very close to the dcm gene, and is essentially restricted to a subset of those genomes that carry dcm. | |
| Parent Property | GenProp0115: DNA repair | |
| Literature References |
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Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| DNA-cytosine methyltransferase | dcm | YES | TIGR00675 (HMM-CLUST): DNA (cytosine-5-)-methyltransferase | |
| very short patch repair | vsr | YES | TIGR00632 (HMM): DNA mismatch endonuclease Vsr |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0115 | DNA repair |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0114 | nucleotide excision repair |
| GenProp0198 | ruvABC Holliday junction complex |
| GenProp0215 | SOS response |
| GenProp0216 | recBCD pathway |
| GenProp0224 | nucleotide excision repair, alternative pathway |
| GenProp0225 | mismatch repair |
| GenProp0227 | excision repair |
| GenProp0228 | direct repair |
| GenProp0491 | recFOR recombination pathway |
| GenProp0492 | nonhomologous end-joining, bacterial type |
| GenProp0493 | addAB pathway |