Genome Property Definition Page
Accession | GenProp0767 | |
Name | very short patch repair | |
Type | SYSTEM | |
Description | Very short patch (VSP) repair is a repair system that recognizes mismatches caused by deamination of 5-methylcytosine (5meC). Cytosine is modified to 5meC by the product of the dcm gene. Vsr is an endonuclease that creates a nick to allow the repair. In Escherichia coli, the second C of the DNA motif CCWGG (where W is A or T) is methylated; deamination yields T:G mispairs reccognized by the vsr gene product. The vsr gene typically is found very close to the dcm gene, and is essentially restricted to a subset of those genomes that carry dcm. | |
Parent Property | GenProp0115: DNA repair | |
Literature References |
|
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
DNA-cytosine methyltransferase | dcm | YES | TIGR00675 (HMM-CLUST): DNA (cytosine-5-)-methyltransferase | |
very short patch repair | vsr | YES | TIGR00632 (HMM): DNA mismatch endonuclease Vsr |
Parent Properties
Accession | Name |
---|---|
GenProp0115 | DNA repair |
Sibling Properties
Accession | Name |
---|---|
GenProp0114 | nucleotide excision repair |
GenProp0198 | ruvABC Holliday junction complex |
GenProp0215 | SOS response |
GenProp0216 | recBCD pathway |
GenProp0224 | nucleotide excision repair, alternative pathway |
GenProp0225 | mismatch repair |
GenProp0227 | excision repair |
GenProp0228 | direct repair |
GenProp0491 | recFOR recombination pathway |
GenProp0492 | nonhomologous end-joining, bacterial type |
GenProp0493 | addAB pathway |
GenProp1099 | 8-oxoguanine DNA repair |