Genome Property Definition Page

AccessionGenProp0769
NameNeisseria lipooligosaccharide, lacto-N-neotetraose biosynthesis
TypePATHWAY
DescriptionIn Neisseria, lipooligosaccharide (LOS) is a highly variable virulence determinant. This Genome Property describes a set of three glycosyltransferases (lgtA, lgtB, and lgtE) that work together in the formation of lacto-N-neotetraose, a component of the LOS alpha chain. Additional genes may also be present and lead to different types of LOS.
JCVI RoleBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Gene Ontology TermGO:0009103: lipopolysaccharide biosynthetic process (biological_process)
GO:0009103: lipopolysaccharide biosynthetic process (biological_process)
GO:0009103: lipopolysaccharide biosynthetic process (biological_process)
GO:0009103: lipopolysaccharide biosynthetic process (biological_process)
GO:0009103: lipopolysaccharide biosynthetic process (biological_process)
GO:0009103: lipopolysaccharide biosynthetic process (biological_process)
GO:0009103: lipopolysaccharide biosynthetic process (biological_process)
GO:0009103: lipopolysaccharide biosynthetic process (biological_process)
GO:0009103: lipopolysaccharide biosynthetic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
lacto-N-neotetraose biosynthesis glycosyl transferase LgtAlgtAYES2122 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process
lacto-N-neotetraose biosynthesis glycosyl transferase LgtAlgtAYES2122 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process
lacto-N-neotetraose biosynthesis glycosyl transferase LgtAlgtAYES2122 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process
lacto-N-neotetraose biosynthesis glycosyl transferase LgtBlgtBYES2120 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process
lacto-N-neotetraose biosynthesis glycosyl transferase LgtBlgtBYES2120 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process
lacto-N-neotetraose biosynthesis glycosyl transferase LgtBlgtBYES2120 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process
lacto-N-neotetraose biosynthesis glycosyl transferase LgtElgtEYES2121 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process
lacto-N-neotetraose biosynthesis glycosyl transferase LgtElgtEYES2121 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process
lacto-N-neotetraose biosynthesis glycosyl transferase LgtElgtEYES2121 (RULE_BASE)
GO:0009103: lipopolysaccharide biosynthetic process