Genome Property Definition Page

AccessionGenProp0776
Namepyochelin biosynthesis
TypeSYSTEM
DescriptionPyochelin is a siderophore derived from salicylate and cysteine. Note that, in Pseudomonas aeruginosa, some of these enzymes also play a role in making the antibiotic dihydroaeruginoate.
JCVI RoleSiderophores
Parent PropertyGenProp0770: siderophore biosynthesis
Literature References
[ 1 ] Reimmann C, Patel HM, Walsh CT, Haas D   PchC thioesterase optimizes nonribosomal biosynthesis of the peptide siderophore pyochelin in Pseudomonas aeruginosa.   J Bacteriol. 2004 Oct;186(19):6367-73.  PMID 15375116
Gene Ontology TermGO:0042864: pyochelin biosynthetic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
isochorismate synthase, PchA familypchAYES2191 (RULE_BASE)
GO:0042864: pyochelin biosynthetic process
isochorismate pyruvate-lyase, PchB familypchBYES2192 (RULE_BASE)
GO:0042864: pyochelin biosynthetic process
pyochelin biosynthesis editing thioesterase PchCpchCYES2194 (RULE_BASE)
GO:0042864: pyochelin biosynthetic process
salicyl-AMP ligase, PchD familypchDYES2188 (RULE_BASE)
GO:0042864: pyochelin biosynthetic process
pyochelin biosynthesis peptide synthase PchEpchEYES2196 (RULE_BASE)
GO:0042864: pyochelin biosynthetic process
pyochelin biosynthesis peptide synthase PchFpchFYES2195 (RULE_BASE)
GO:0042864: pyochelin biosynthetic process

Parent Properties
AccessionName
GenProp0770siderophore biosynthesis


Sibling Properties
AccessionName
GenProp0771enterobactin (enterochelin) biosynthesis
GenProp0772yersiniabactin biosynthesis
GenProp0773aerobactin biosynthesis
GenProp0775mycobactin biosynthesis
GenProp0777staphylobactin biosynthesis
GenProp0783petrobactin biosynthesis