Genome Property Definition Page

Nameproteasome, bacterial
DescriptionThe proteasome, a large complex formed of alpha and beta subunits, performs protein degradation in eukaryotes, archaea, and bacteria. This Genome Property describes a bacterial 20S proteasome that approximates being restricted to and universal in the Actinobacteria. Nearly all bacterial with this proteasomal system use pupylation to tag proteins as proteasomal targets. The HslVU system in many bacteria is related, with HslV homologous to the proteasome beta subunit, but that system is outside the scope of the archaeal-type bacterial 20S proteasome described here.
JCVI RoleDegradation of proteins, peptides, and glycopeptides
Parent PropertyGenProp0301: protein degradation
Gene Ontology TermGO:0010498: proteasomal protein catabolic process (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
proteasome, alpha subunitprcAYESTIGR03691 (HMM): proteasome, alpha subunitGO:0010498: proteasomal protein catabolic process
proteasome, beta subunitprcBYESTIGR03690 (HMM): proteasome, beta subunitGO:0010498: proteasomal protein catabolic process

Parent Properties
GenProp0301protein degradation

Sibling Properties
GenProp0211tmRNA trans-translation system
GenProp0251clpXP degradation machine
GenProp0684FtsH/HflKC protease complex
GenProp0833proteasome-targeting modification by pupylation
GenProp0835ATP-dependent protease HslVU