• Genome Properties List
• Top Level Genome Properties

Genome Property Definition Page

Accession	GenProp0835
Name	ATP-dependent protease HslVU
Type	SYSTEM
Description	HslVU, also known as ClpQY, is an ATP-dependent protease that resembles proteasomes. The ATPase HslU acts in protein unfolding, while the threonine-type endopeptidase HslV is homologous to the proteasome beta subunit and acts in protein degradation. Members of this family frequently are described as heat shock proteins.
JCVI Role	Degradation of proteins, peptides, and glycopeptides
Parent Property	GenProp0301: protein degradation
Literature References	[ 1 ] Seol JH, Yoo SJ, Shin DH, Shim YK, Kang MS, Goldberg AL, Chung CH   The heat-shock protein HslVU from Escherichia coli is a protein-activated ATPase as well as an ATP-dependent proteinase.   Eur J Biochem. 1997 Aug 1;247(3):1143-50.  PMID 9288941
Gene Ontology Term	GO:0006510: ATP-dependent proteolysis (biological_process)

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
ATP-dependent protease HslVU, ATPase subunit	hslU	YES	TIGR00390 (HMM): ATP-dependent protease HslVU, ATPase subunit	GO:0006510: ATP-dependent proteolysis
ATP-dependent protease HslVU, peptidase subunit	hslV	YES	TIGR03692 (HMM): ATP-dependent protease HslVU, peptidase subunit	GO:0006510: ATP-dependent proteolysis

Parent Properties

Accession	Name
GenProp0301	protein degradation

Sibling Properties

Accession	Name
GenProp0211	tmRNA trans-translation system
GenProp0251	clpXP degradation machine
GenProp0684	FtsH/HflKC protease complex
GenProp0833	proteasome-targeting modification by pupylation
GenProp0834	proteasome, bacterial