Genome Property Definition Page

AccessionGenProp0862
Namepyridoxal phosphate biosynthesis, PdxA/PdxJ pathway
TypePATHWAY
DescriptionThis genome property represents pyridoxal 5-prime phosphate biosynthesis as it occurs in Escherichia coli, from deoxyxylulose 5-phosphate and 4-phosphohydroxy-L-threonine. The key proteins are PdxA and PdxJ. This pathway contrasts with the Pdx1 and Pdx2 pathway, as found in Bacillus subtilis. The current version of this Genome Property assesses only the two signature enzymes PdxA and PdxJ.
JCVI RolePantothenate and coenzyme A
Parent PropertyGenProp0184: cofactor biosynthesis
Gene Ontology TermGO:0042823: pyridoxal phosphate biosynthetic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
4-hydroxythreonine-4-phosphate dehydrogenasepdxAYESTIGR00557 (HMM): 4-hydroxythreonine-4-phosphate dehydrogenase PdxAGO:0042823: pyridoxal phosphate biosynthetic process
erythronate-4-phosphate dehydrogenasepdxBNO
pyridoxal phosphate synthasepdxJYESTIGR00559 (HMM): pyridoxine 5'-phosphate synthaseGO:0042823: pyridoxal phosphate biosynthetic process

Parent Properties
AccessionName
GenProp0184cofactor biosynthesis


Sibling Properties
AccessionName
GenProp0001chorismate biosynthesis via shikimate
GenProp0030glutathione biosynthesis
GenProp0036biotin biosynthesis
GenProp0038tetrahydrofolate biosynthesis from GTP and PABA
GenProp0057NAD(P) biosynthesis from L-aspartate and DHAP
GenProp0112riboflavin, FAD and FMN from GTP and ribulose-5-P
GenProp0124pantothenate biosynthesis from aspartate and 2-oxoisovalerate
GenProp0136ubiquinone biosynthesis from chorismate, aerobic
GenProp0140iron-sulfur cluster assembly systems
GenProp0170coenzyme PQQ biosynthesis
GenProp0171coenzyme A biosynthesis from pantothenate
GenProp0194siroheme biosynthesis from uroporphrinogen-III
GenProp0220uroporhyrinogen III biosynthesis from 5-aminolevulinate
GenProp0221protoporphyrin IX biosynthesis from uroporphyrinogen III
GenProp0222protoheme from protoporphyrin IX
GenProp0250thiamine: hydroxyethylthiazole from 1-deoxy-D-xylulose-5-phosphate, cysteine, either Tyr or Gly
GenProp02555-aminolevulinate biosynthesis
GenProp0261thiamin pyrophosphate (TPP) de novo biosynthesis
GenProp0274coenzyme B12 biosynthesis - overview
GenProp0300photosynthetic cofactor biosynthesis
GenProp0466molybdopterin biosynthesis
GenProp0752ergothioneine biosynthesis
GenProp0753mycothiol biosynthesis
GenProp0759para-aminobenzoic acid (PABA) biosynthesis from chorismate
GenProp0791coenzyme F420 biosynthesis
GenProp07927,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) biosynthesis
GenProp0836menaquinone biosynthesis
GenProp0860tryptophan tryptophylquinone modification of methylamine dehydrogenase
GenProp0863pyridoxal phosphate biosynthesis, Pdx1/Pdx2 pathway
GenProp0891coenzyme M biosynthesis
GenProp0917mycofactocin system
GenProp0927bacillithiol biosynthesis
GenProp1064ovothiol biosynthesis