Genome Property Definition Page

AccessionGenProp0869
Namedecarboxylation/antiport proton-motive cycle: arginine-agmatine
TypeSYSTEM
DescriptionThis Genome Property represents a proton-motive cycle. A cycle of decarboxylating an arginine to agmatine plus CO2, then exchanging the cytosolic agmatine for an extracellular arginine, has the net effect of consuming one proton. The Chlamydophila pneumoniae system, unlike the E. coli system, has a third component, and outer membrane porin. Analogous systems for antiport of substrates related by decarboxylation include, for example, the pairing of an asparate decarboxylase with an aspartate-alanine antiporter, as in Tetragenococcus halophila.
Parent PropertyGenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
GenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
GenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
Literature References
[ 1 ] Smith CB, Graham DE   Outer and inner membrane proteins compose an arginine-agmatine exchange system in Chlamydophila pneumoniae.   J Bacteriol. 2008 Nov;190(22):7431-40.  PMID 18790867
[ 2 ] Andrell J, Hicks MG, Palmer T, Carpenter EP, Iwata S, Maher MJ   Crystal structure of the acid-induced arginine decarboxylase from Escherichia coli: reversible decamer assembly controls enzyme activity.   Biochemistry. 2009 May 12;48(18):3915-27.  PMID 19298070
[ 1 ] Smith CB, Graham DE   Outer and inner membrane proteins compose an arginine-agmatine exchange system in Chlamydophila pneumoniae.   J Bacteriol. 2008 Nov;190(22):7431-40.  PMID 18790867
[ 2 ] Andrell J, Hicks MG, Palmer T, Carpenter EP, Iwata S, Maher MJ   Crystal structure of the acid-induced arginine decarboxylase from Escherichia coli: reversible decamer assembly controls enzyme activity.   Biochemistry. 2009 May 12;48(18):3915-27.  PMID 19298070
[ 1 ] Smith CB, Graham DE   Outer and inner membrane proteins compose an arginine-agmatine exchange system in Chlamydophila pneumoniae.   J Bacteriol. 2008 Nov;190(22):7431-40.  PMID 18790867
[ 2 ] Andrell J, Hicks MG, Palmer T, Carpenter EP, Iwata S, Maher MJ   Crystal structure of the acid-induced arginine decarboxylase from Escherichia coli: reversible decamer assembly controls enzyme activity.   Biochemistry. 2009 May 12;48(18):3915-27.  PMID 19298070
Gene Ontology TermGO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
arginine/agmatine exchange system porinaaxANO2638 (RULE_BASE)

2638 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
arginine/agmatine exchange system porinaaxANO2638 (RULE_BASE)

2638 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
arginine/agmatine exchange system porinaaxANO2638 (RULE_BASE)

2638 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
arginine decarboxylase, acid-inducedadiAYES2635 (RULE_BASE)

2636 (RULE_BASE)

2635 (RULE_BASE)

2636 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
arginine decarboxylase, acid-inducedadiAYES2635 (RULE_BASE)

2636 (RULE_BASE)

2635 (RULE_BASE)

2636 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
arginine decarboxylase, acid-inducedadiAYES2635 (RULE_BASE)

2636 (RULE_BASE)

2635 (RULE_BASE)

2636 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
arginine/agmatine antiporteradiCYES2634 (RULE_BASE)

2637 (RULE_BASE)

2634 (RULE_BASE)

2637 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
arginine/agmatine antiporteradiCYES2634 (RULE_BASE)

2637 (RULE_BASE)

2634 (RULE_BASE)

2637 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
arginine/agmatine antiporteradiCYES2634 (RULE_BASE)

2637 (RULE_BASE)

2634 (RULE_BASE)

2637 (RULE_BASE)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient

Parent Properties
AccessionName
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment


Sibling Properties
AccessionName
GenProp0639arginine degradation via citrulline, ATP-generating
GenProp0867decarboxylation/antiport proton-motive cycle: aspartate-alanine
GenProp0870decarboxylation/antiport proton-motive cycle: lysine-cadaverine
GenProp0871decarboxylation/antiport proton-motive cycle: ornithine-putrescine
GenProp0872decarboxylation/antiport proton-motive cycle: histidine-histamine
GenProp0875decarboxylation/antiport proton-motive cycle: tyrosine-tyramine
GenProp0876decarboxylation/antiport proton-motive cycle: glutamate-GABA
GenProp1034decarboxylation/antiport proton-motive cycle: oxalate-formate