Genome Property Definition Page

AccessionGenProp0871
Namedecarboxylation/antiport proton-motive cycle: ornithine-putrescine
TypeSYSTEM
DescriptionThe decarboxylation of L-ornithine to putrescine consumes a proton. Exchange of putrescine for L-ornithine by an antiporter completes a cycle that effectively removes a cytosolic protein. Decarboxylation/antiporter systems for this and other (e.g. aspartate-alanine) substrate pairs can provide protection against acidic pH.
JCVI RoleAdaptations to atypical conditions
Parent PropertyGenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
GenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
GenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
Literature References
[ 1 ] Kashiwagi K, Miyamoto S, Suzuki F, Kobayashi H, Igarashi K   Excretion of putrescine by the putrescine-ornithine antiporter encoded by the potE gene of Escherichia coli.   Proc Natl Acad Sci U S A. 1992 May 15;89(10):4529-33.  PMID 1584788
[ 2 ] de las Rivas B, Marcobal A, Munoz R   Gene organization of the ornithine decarboxylase-encoding region in Morganella morganii.   J Appl Microbiol. 2007 Jun;102(6):1551-60.  PMID 17578420
[ 3 ]Romano A, Trip H, Lonvaud-Funel A, Lolkema JS, Lucas PM  Evidence of two functionally distinct ornithine decarboxylation systems in lactic acid bacteria.  Appl Environ Microbiol. 2012 Mar;78(6):1953-61.  PMID 22247134
[ 1 ] Kashiwagi K, Miyamoto S, Suzuki F, Kobayashi H, Igarashi K   Excretion of putrescine by the putrescine-ornithine antiporter encoded by the potE gene of Escherichia coli.   Proc Natl Acad Sci U S A. 1992 May 15;89(10):4529-33.  PMID 1584788
[ 2 ] de las Rivas B, Marcobal A, Munoz R   Gene organization of the ornithine decarboxylase-encoding region in Morganella morganii.   J Appl Microbiol. 2007 Jun;102(6):1551-60.  PMID 17578420
[ 3 ]Romano A, Trip H, Lonvaud-Funel A, Lolkema JS, Lucas PM  Evidence of two functionally distinct ornithine decarboxylation systems in lactic acid bacteria.  Appl Environ Microbiol. 2012 Mar;78(6):1953-61.  PMID 22247134
[ 1 ] Kashiwagi K, Miyamoto S, Suzuki F, Kobayashi H, Igarashi K   Excretion of putrescine by the putrescine-ornithine antiporter encoded by the potE gene of Escherichia coli.   Proc Natl Acad Sci U S A. 1992 May 15;89(10):4529-33.  PMID 1584788
[ 2 ] de las Rivas B, Marcobal A, Munoz R   Gene organization of the ornithine decarboxylase-encoding region in Morganella morganii.   J Appl Microbiol. 2007 Jun;102(6):1551-60.  PMID 17578420
[ 3 ]Romano A, Trip H, Lonvaud-Funel A, Lolkema JS, Lucas PM  Evidence of two functionally distinct ornithine decarboxylation systems in lactic acid bacteria.  Appl Environ Microbiol. 2012 Mar;78(6):1953-61.  PMID 22247134
Gene Ontology TermGO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
ornithine-putrescine antiporterPotEYES2647 (RULE_BASE)

TIGR04299 (HMM): putrescine-ornithine antiporter
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
ornithine-putrescine antiporterPotEYES2647 (RULE_BASE)

TIGR04299 (HMM): putrescine-ornithine antiporter
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
ornithine-putrescine antiporterPotEYES2647 (RULE_BASE)

TIGR04299 (HMM): putrescine-ornithine antiporter
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
ornithine decarboxylaseSpeFYES2646 (RULE_BASE)

TIGR04301 (HMM): ornithine decarboxylase SpeF
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
ornithine decarboxylaseSpeFYES2646 (RULE_BASE)

TIGR04301 (HMM): ornithine decarboxylase SpeF
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
ornithine decarboxylaseSpeFYES2646 (RULE_BASE)

TIGR04301 (HMM): ornithine decarboxylase SpeF
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient

Parent Properties
AccessionName
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment


Sibling Properties
AccessionName
GenProp0639arginine degradation via citrulline, ATP-generating
GenProp0867decarboxylation/antiport proton-motive cycle: aspartate-alanine
GenProp0869decarboxylation/antiport proton-motive cycle: arginine-agmatine
GenProp0870decarboxylation/antiport proton-motive cycle: lysine-cadaverine
GenProp0872decarboxylation/antiport proton-motive cycle: histidine-histamine
GenProp0875decarboxylation/antiport proton-motive cycle: tyrosine-tyramine
GenProp0876decarboxylation/antiport proton-motive cycle: glutamate-GABA
GenProp1034decarboxylation/antiport proton-motive cycle: oxalate-formate