Genome Property Definition Page

AccessionGenProp0872
Namedecarboxylation/antiport proton-motive cycle: histidine-histamine
TypeSYSTEM
DescriptionThe decarboxylation of histidine to histamine consumes a proton. Exchange of histamine for histadine by an antiporter completes a cycle that effectively removes a cytosolic proton. Decarboxylation/antiporter systems for this and other (e.g. aspartate-alanine) substrate pairs can provide protection against acidic pH.
JCVI RoleAdaptations to atypical conditions
Parent PropertyGenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
GenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
GenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
Literature References
[ 1 ] Martin MC, Fernandez M, Linares DM, Alvarez MA   Sequencing, characterization and transcriptional analysis of the histidine decarboxylase operon of Lactobacillus buchneri.   Microbiology. 2005 Apr;151(Pt 4):1219-28  PMID 15817789
[ 1 ] Martin MC, Fernandez M, Linares DM, Alvarez MA   Sequencing, characterization and transcriptional analysis of the histidine decarboxylase operon of Lactobacillus buchneri.   Microbiology. 2005 Apr;151(Pt 4):1219-28  PMID 15817789
[ 1 ] Martin MC, Fernandez M, Linares DM, Alvarez MA   Sequencing, characterization and transcriptional analysis of the histidine decarboxylase operon of Lactobacillus buchneri.   Microbiology. 2005 Apr;151(Pt 4):1219-28  PMID 15817789
Gene Ontology TermGO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
histidine decarboxylaseHdcAYESTIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
TIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
TIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
histidine decarboxylaseHdcAYESTIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
TIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
TIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
histidine decarboxylaseHdcAYESTIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
TIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
TIGR00541 (HMM): histidine decarboxylase, pyruvoyl type
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
histidine-histamine antiporterHdcCYES2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
histidine-histamine antiporterHdcCYES2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
histidine-histamine antiporterHdcCYES2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
2639 (RULE_BASE)

2642 (RULE_BASE)

TIGR04298 (HMM): histidine-histamine antiporter
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient

Parent Properties
AccessionName
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment
GenProp0873ion-motive antiporter cycles
GenProp0874response to acid (low pH) environment


Sibling Properties
AccessionName
GenProp0639arginine degradation via citrulline, ATP-generating
GenProp0867decarboxylation/antiport proton-motive cycle: aspartate-alanine
GenProp0869decarboxylation/antiport proton-motive cycle: arginine-agmatine
GenProp0870decarboxylation/antiport proton-motive cycle: lysine-cadaverine
GenProp0871decarboxylation/antiport proton-motive cycle: ornithine-putrescine
GenProp0875decarboxylation/antiport proton-motive cycle: tyrosine-tyramine
GenProp0876decarboxylation/antiport proton-motive cycle: glutamate-GABA
GenProp1034decarboxylation/antiport proton-motive cycle: oxalate-formate