Genome Property Definition Page
Accession | GenProp0890 | |
Name | copper homeostasis system CopRS/CopABCD | |
Type | SYSTEM | |
Description | This property describes a copper resistance (or copper homeostasis) system. The CopA/CopB pair has been shown in Xanthomonas axonopodis pathovar citri to be necessary for copper resistance. The CopC/CopD pair, occasionally found fused, has been implicated in copper resistance in some species, copper uptake in others. These two pairs commonly occur independently but occasionally occur together. CopS and CopR are copper-sensing histidine kinase and DNA-binding response regulator. | |
JCVI Role | Adaptations to atypical conditions | |
Literature References |
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Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
copper-resistance protein, CopA family | copA | YES | TIGR01480 (HMM): copper-resistance protein, CopA family | |
copper-resistance protein, CopB family | copB | YES | PF05275 (HMM): copper resistance protein B precursor CopB | |
copper resistance protein, CopC family | copC | YES | PF04234 (HMM): CopC domain | |
copper resistance protein, CopD family | copD | YES | PF05425 (HMM): copper resistance protein D | |
copper resistance response regulator | copR | NO | 2679 (RULE_BASE) | |
heavy metal sensor kinase | copS | YES | TIGR01386 (HMM): heavy metal sensor kinase |