Genome Property Definition Page

Namealcohol ABC transporter, PedABC-type
DescriptionA conserved four-gene operon, found regularly in genomes with PQQ biosynthesis and with PQQ-dependent enzymes for catabolism of various alcohols, appears to represent an alcohol import ABC transporter. This conclusion is based partly on recognizing one member of the operon as a likely periplasmic substrate-binding protein. An earlier view (PMID:18177365) imagines this system to be an efflux transporter for removal of toxic intermediates during catabolism.
JCVI RoleCarbohydrates, organic alcohols, and acids
Parent PropertyGenProp0071: transport
Literature References
[ 1 ] Arias S, Olivera ER, Arcos M, Naharro G, Luengo JM   Genetic analyses and molecular characterization of the pathways involved in the conversion of 2-phenylethylamine and 2-phenylethanol into phenylacetic acid in Pseudomonas putida U.   Environ Microbiol. 2008 Feb;10(2):413-32. Epub 2007 Dec 27.  PMID 18177365

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
alcohol ABC transporter, substrate-binding subunitPQQbindYESTIGR03863 (HMM): ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system
alcohol ABC transporter, beta-propeller proteinPQQpedAYESTIGR03866 (HMM): PQQ-dependent catabolism-associated beta-propeller protein
alcohol ABC transporter, ATP-binding subunitPQQpedBYESTIGR03864 (HMM): ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system
alcohol ABC transporter, permease subunitPQQpedCYESTIGR03861 (HMM): alcohol ABC transporter, permease protein

Parent Properties

Sibling Properties
GenProp0179protein transport
GenProp0180small molecule transport
GenProp0489F-type conjugation system
GenProp0649heterocyst-related ABC exporter DevBCA
GenProp0821putative Na:solute symporter two-gene cassette
GenProp0857anchored repeat-class ABC transporter, P. acnes type
GenProp0941TonB-dependent nutrient uptake pairs, RagAB/SusCD type
GenProp1094energy-coupling factor transporters