Genome Property Definition Page

AccessionGenProp0906
Namepoly-beta-1,6 N-acetyl-D-glucosamine system, IcaADBC type
TypeSYSTEM
DescriptionMany pathogenic bacteria produce an exopolysaccharide based on poly-N-acetylglucosamine. It is an important factor in biofilm formation and therefore virulence. Modifications (as by polysaccharide N-deacetylase) and attachments differ from system to system. This Genome Property describes the variant associated with the IcaADBC operon as found in Staphylococcus epidermidis. Biosynthesis begins with UDP-N-acetylglucosamine, polymerized with beta-1,6 linkages, followed by incomplete deacetylation.
JCVI RoleBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Parent PropertyGenProp0186: storage and structural polymer biosynthesis
GenProp0186: storage and structural polymer biosynthesis
Gene Ontology TermGO:0045226: extracellular polysaccharide biosynthetic process (biological_process)
GO:0045226: extracellular polysaccharide biosynthetic process (biological_process)
GO:0045226: extracellular polysaccharide biosynthetic process (biological_process)
GO:0045226: extracellular polysaccharide biosynthetic process (biological_process)
GO:0045226: extracellular polysaccharide biosynthetic process (biological_process)
GO:0045226: extracellular polysaccharide biosynthetic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
intercellular adhesin protein AicaAYES2726 (RULE_BASE)
GO:0045226: extracellular polysaccharide biosynthetic process
intercellular adhesin protein AicaAYES2726 (RULE_BASE)
GO:0045226: extracellular polysaccharide biosynthetic process
intercellular adhesin protein BicaBYESTIGR03933 (HMM): intercellular adhesin biosynthesis polysaccharide N-deacetylaseGO:0045226: extracellular polysaccharide biosynthetic process
intercellular adhesin protein BicaBYESTIGR03933 (HMM): intercellular adhesin biosynthesis polysaccharide N-deacetylaseGO:0045226: extracellular polysaccharide biosynthetic process
intercellular adhesin protein CicaCYES2728 (RULE_BASE)
GO:0045226: extracellular polysaccharide biosynthetic process
intercellular adhesin protein CicaCYES2728 (RULE_BASE)
GO:0045226: extracellular polysaccharide biosynthetic process
intercellular adhesin protein DicaDYESTIGR03932 (HMM): intracellular adhesion protein DGO:0045226: extracellular polysaccharide biosynthetic process
intercellular adhesin protein DicaDYESTIGR03932 (HMM): intracellular adhesion protein DGO:0045226: extracellular polysaccharide biosynthetic process
intercellular adhesin regulatoricaRNO2727 (RULE_BASE)
intercellular adhesin regulatoricaRNO2727 (RULE_BASE)

Parent Properties
AccessionName
GenProp0186storage and structural polymer biosynthesis
GenProp0186storage and structural polymer biosynthesis


Sibling Properties
AccessionName
GenProp0055polyhydroxyalkanoic acids
GenProp0156cyanophycin-like storage polymers
GenProp0158peptidoglycan(murein) biosynthesis
GenProp0168glycogen system
GenProp0183dTDP-L-rhamnose biosynthesis from dTDP-4-dehydro-L-rhamnose
GenProp0297lipopolysaccharide biosynthesis
GenProp0652exopolysaccharide biosynthesis, exosortase A-associated
GenProp0655exopolysaccharide biosynthesis, exosortase B-associated
GenProp0658cellulose biosynthesis
GenProp0793CMP-N-acetylneuraminate biosynthesis from UDP-N-acetylglucosamine
GenProp0822poly(gamma-glutamic acid) biosynthesis
GenProp0907poly-beta-1,6 N-acetyl-D-glucosamine system, PgaABCD type