Genome Property Definition Page
Accession | GenProp0915 | |
Name | hydrogenase, mono-iron type | |
Type | SYSTEM | |
Description | This property describes 5,10-methenyltetrahydromethanopterin hydrogenase (HmdA), also called mono-iron hydrogenase or iron-sulfur cluster-free hydrogenase, together with a few of its accessory proteins: HmdB (a radical SAM protein) and HmdC. The enzyme contains a novel cofactor with an Fe ion ligated by two CO molecules, a cysteine side chain, a guanylyl pyridinol cofactor, and an uncharacterized additional ligand. | |
JCVI Role | Methanogenesis | |
Parent Property | GenProp0070: energy metabolism | |
Literature References |
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Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
5,10-methenyltetrahydromethanopterin hydrogenase | hmdA | YES | TIGR01723 (HMM): 5,10-methenyltetrahydromethanopterin hydrogenase | |
HmdA cofactor biosynthesis rSAM protein HmdB | hmdB | YES | TIGR03957 (HMM): 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB | |
HmdA cofactor biosynthesis protein HmdC | hmdC | YES | TIGR03958 (HMM): 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC |
Parent Properties
Accession | Name |
---|---|
GenProp0070 | energy metabolism |
Sibling Properties
Accession | Name |
---|---|
GenProp0011 | methanogenesis |
GenProp0023 | glyoxylate shunt |
GenProp0027 | photosynthesis |
GenProp0033 | TCA cycle |
GenProp0120 | pentose phosphate cycle |
GenProp0131 | electron transport |
GenProp0243 | ATP synthases |
GenProp0298 | fermentation |
GenProp0459 | D-xylose utilization (conversion to D-xylulose-5-phosphate) |
GenProp0468 | Entner-Doudoroff pathway |
GenProp0473 | arsenite oxidase |
GenProp0611 | aerobic respiration |
GenProp0636 | respiratory nitrate reductase |
GenProp0637 | anaerobic dimethyl sulfoxide reductase |
GenProp0638 | trimethylamine N-oxide reductase system |
GenProp0682 | formate-dependent nitrite reductase, seven-gene type |
GenProp0683 | cytochrome c nitrite reductase NrfHA |
GenProp0691 | glycolysis |
GenProp0695 | cytochrome b558/566 |
GenProp0723 | hydrogenase, nickel and F420-dependent |
GenProp0737 | anaerobic glycerol-3-phosphate dehydrogenase complex |
GenProp0755 | pyruvate conversion to propionate, anaerobic, FAD/NAD-regenerating |
GenProp0756 | fumarate reductase complex |
GenProp0764 | DMSO reductase family type II enzyme |
GenProp0841 | 2-oxoacid:ferredoxin oxidoreductase |
GenProp0856 | bacterio-opsin system |
GenProp0914 | hydrogenase, [FeFe]-dependent |
GenProp1089 | B12-dependent trimeric diol/glycerol dehydratase |
GenProp1101 | quinoprotein cytochrome relay system |