Genome Property Definition Page

AccessionGenProp0933
Namebacillithiol utilization
TypeGUILD
DescriptionThis property describes the guild of proteins dependent on bacillithiol in microbial genomes.Bacillithiol, a thiol analog of glutathione and mycothiol, is a 398-Da alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. A separate property (GenProp0927) describes the biosynthesis of bacillithiol.
Parent PropertyGenProp0075: protein modification, prosthetic groups and cofactors
Literature References
[ 1 ]Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD  Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.  Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6. Epub 2010 Mar 22.  PMID 20308541
Gene Ontology TermGO:0071792: bacillithiol metabolic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
putative bacillithiol TDOR, YpdA familyB_YpdANOTIGR04018 (HMM): putative bacillithiol system oxidoreductase, YpdA familyGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YphP/YqiW familyB_YphPNOPF06491 (HMM): disulphide isomeraseGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YtxJ familyB_YtxJNOTIGR04019 (HMM): bacillithiol system protein YtxJGO:0071792: bacillithiol metabolic process

Parent Properties
AccessionName
GenProp0075protein modification, prosthetic groups and cofactors


Sibling Properties
AccessionName
GenProp0002coenzyme F420 utilization
GenProp0016selenocysteine system
GenProp0061lipoprotein system lgt/lsp/lnt
GenProp0127Tat (Sec-independent) protein export
GenProp0284cobalamin-utilizing enzymes
GenProp0295prokaryotic N-terminal cleavage/methylation, type IV pilin-like
GenProp0726selenium-dependent molybdenum hydroxylase system
GenProp0745lipoyl-protein attachment
GenProp0860tryptophan tryptophylquinone modification of methylamine dehydrogenase
GenProp0918anaerobic sulfatase/maturase system
GenProp0923mycothiol system
GenProp0938glycine radical enzyme system, YjjI/YjjW pair
GenProp0943pyruvate formate-lyase system
GenProp1080protein O-heptosyltransferase with autotransporter target