Genome Property Definition Page

AccessionGenProp0933
Namebacillithiol utilization
TypeGUILD
DescriptionThis property describes the guild of proteins dependent on bacillithiol in microbial genomes.Bacillithiol, a thiol analog of glutathione and mycothiol, is a 398-Da alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. A separate property (GenProp0927) describes the biosynthesis of bacillithiol.
Parent PropertyGenProp0075: protein modification, prosthetic groups and cofactors
GenProp0075: protein modification, prosthetic groups and cofactors
GenProp0075: protein modification, prosthetic groups and cofactors
Literature References
[ 1 ]Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD  Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.  Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6. Epub 2010 Mar 22.  PMID 20308541
[ 1 ]Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD  Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.  Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6. Epub 2010 Mar 22.  PMID 20308541
[ 1 ]Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD  Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.  Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6. Epub 2010 Mar 22.  PMID 20308541
Gene Ontology TermGO:0071792: bacillithiol metabolic process (biological_process)
GO:0071792: bacillithiol metabolic process (biological_process)
GO:0071792: bacillithiol metabolic process (biological_process)
GO:0071792: bacillithiol metabolic process (biological_process)
GO:0071792: bacillithiol metabolic process (biological_process)
GO:0071792: bacillithiol metabolic process (biological_process)
GO:0071792: bacillithiol metabolic process (biological_process)
GO:0071792: bacillithiol metabolic process (biological_process)
GO:0071792: bacillithiol metabolic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
putative bacillithiol TDOR, YpdA familyB_YpdANOTIGR04018 (HMM): putative bacillithiol system oxidoreductase, YpdA familyGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YpdA familyB_YpdANOTIGR04018 (HMM): putative bacillithiol system oxidoreductase, YpdA familyGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YpdA familyB_YpdANOTIGR04018 (HMM): putative bacillithiol system oxidoreductase, YpdA familyGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YphP/YqiW familyB_YphPNOPF06491 (HMM): disulphide isomeraseGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YphP/YqiW familyB_YphPNOPF06491 (HMM): disulphide isomeraseGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YphP/YqiW familyB_YphPNOPF06491 (HMM): disulphide isomeraseGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YtxJ familyB_YtxJNOTIGR04019 (HMM): bacillithiol system protein YtxJGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YtxJ familyB_YtxJNOTIGR04019 (HMM): bacillithiol system protein YtxJGO:0071792: bacillithiol metabolic process
putative bacillithiol TDOR, YtxJ familyB_YtxJNOTIGR04019 (HMM): bacillithiol system protein YtxJGO:0071792: bacillithiol metabolic process

Parent Properties
AccessionName
GenProp0075protein modification, prosthetic groups and cofactors
GenProp0075protein modification, prosthetic groups and cofactors
GenProp0075protein modification, prosthetic groups and cofactors


Sibling Properties
AccessionName
GenProp0002coenzyme F420 utilization
GenProp0016selenocysteine system
GenProp0061lipoprotein system lgt/lsp/lnt
GenProp0127Tat (Sec-independent) protein export
GenProp0284cobalamin-utilizing enzymes
GenProp0295prokaryotic N-terminal cleavage/methylation, type IV pilin-like
GenProp0726selenium-dependent molybdenum hydroxylase system
GenProp0745lipoyl-protein attachment
GenProp0860tryptophan tryptophylquinone modification of methylamine dehydrogenase
GenProp0918anaerobic sulfatase/maturase system
GenProp0923mycothiol system
GenProp0938glycine radical enzyme system, YjjI/YjjW pair
GenProp0943pyruvate formate-lyase system