Genome Property Definition Page

AccessionGenProp0942
Namealkane biosynthesis, cyanobacterial
TypePATHWAY
DescriptionThis two gene system converts even-numbered saturated and unsaturated fatty acids (largely C16 and C18) into n-1 odd-numbered alkanes or alkenes [1]. The most commonly observed alkanes in cyanobacteria, where this system is found, are heptadecane, pentadecane and methyl-heptadecane [1]. Fatty acyl-acyl carrier protein (ACP) substrates are first converted to fatty aldehydes by the action of an NAD(P)H-dependent Acyl-ACP reductase. This reductase is distantly related to the short-chain dehydrogenase or reductase (SDR) family (PF00106). The fatty aldehyde is subsequently converted to hydrocarbons by an aldehyde decarbonylase, releasing CO. This decarbonylase is distantly related to a family of di-iron-containing reductases including ribonucleotide reductase.
Parent PropertyGenProp0063: biosynthesis
GenProp0063: biosynthesis
GenProp0063: biosynthesis
Literature References
[ 1 ]Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB  Microbial biosynthesis of alkanes.  Science. 2010 Jul 30;329(5991):559-62.  PMID 20671186
[ 1 ]Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB  Microbial biosynthesis of alkanes.  Science. 2010 Jul 30;329(5991):559-62.  PMID 20671186
[ 1 ]Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB  Microbial biosynthesis of alkanes.  Science. 2010 Jul 30;329(5991):559-62.  PMID 20671186
Gene Ontology TermGO:0043447: alkane biosynthetic process (biological_process)
GO:0043447: alkane biosynthetic process (biological_process)
GO:0043447: alkane biosynthetic process (biological_process)
GO:0043447: alkane biosynthetic process (biological_process)
GO:0043447: alkane biosynthetic process (biological_process)
GO:0043447: alkane biosynthetic process (biological_process)
GO:0043447: alkane biosynthetic process (biological_process)
GO:0043447: alkane biosynthetic process (biological_process)
GO:0043447: alkane biosynthetic process (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
acyl-ACP reductaseAcACP_RYESTIGR04058 (HMM): long-chain fatty acyl-ACP reductase (aldehyde-forming)GO:0043447: alkane biosynthetic process
acyl-ACP reductaseAcACP_RYESTIGR04058 (HMM): long-chain fatty acyl-ACP reductase (aldehyde-forming)GO:0043447: alkane biosynthetic process
acyl-ACP reductaseAcACP_RYESTIGR04058 (HMM): long-chain fatty acyl-ACP reductase (aldehyde-forming)GO:0043447: alkane biosynthetic process
aldehyde decarbonylaseAl_DeCOYESTIGR04059 (HMM): long-chain fatty aldehyde decarbonylaseGO:0043447: alkane biosynthetic process
aldehyde decarbonylaseAl_DeCOYESTIGR04059 (HMM): long-chain fatty aldehyde decarbonylaseGO:0043447: alkane biosynthetic process
aldehyde decarbonylaseAl_DeCOYESTIGR04059 (HMM): long-chain fatty aldehyde decarbonylaseGO:0043447: alkane biosynthetic process

Parent Properties
AccessionName
GenProp0063biosynthesis
GenProp0063biosynthesis
GenProp0063biosynthesis


Sibling Properties
AccessionName
GenProp0077natural products biosynthesis
GenProp0126amino acid biosynthesis
GenProp0184cofactor biosynthesis
GenProp0185nucleotide biosynthesis
GenProp0186storage and structural polymer biosynthesis
GenProp0197protein biosynthesis
GenProp0219spermidine biosynthesis from arginine (via agmatine)
GenProp0267osmolyte biosynthesis
GenProp0641spermidine biosynthesis from putrescine and S-adenosylmethionine
GenProp0642putrescine biosynthesis from arginine utilizing agmatinase
GenProp0643putrescine biosynthesis from arginine via ornithine
GenProp0644putrescine biosynthesis from glutamate via ornithine
GenProp0645putrescine biosynthesis
GenProp0724phosphonoacetaldehyde biosynthesis from phosphoenolpyruvate
GenProp0738agmatine to putrescine via N-carbamoylputrescine
GenProp0795carbohydrate biosynthesis
GenProp0838lipid biosynthesis
GenProp0909capreomycidine biosynthesis
GenProp1053rSAM/selenodomain system
GenProp1056rhizo-twelve system
GenProp1057radical SAM/SPASM system GeoRSP